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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR7A3
All Species:
17.58
Human Site:
Y49
Identified Species:
48.33
UniProt:
O95154
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95154
NP_036199.2
331
37206
Y49
E
I
D
T
A
F
V
Y
S
E
G
Q
S
E
T
Chimpanzee
Pan troglodytes
XP_001159016
331
36820
Y49
E
I
D
T
A
F
L
Y
S
D
G
Q
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001105933
377
41710
Y95
E
I
D
T
A
F
V
Y
S
D
G
Q
S
E
T
Dog
Lupus familis
XP_535385
371
40597
Y89
E
L
D
T
A
F
M
Y
S
D
G
Q
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG76
367
40580
Y85
E
L
D
T
A
F
M
Y
C
D
G
Q
S
E
N
Rat
Rattus norvegicus
P38918
327
36729
Q49
A
F
V
Y
A
N
G
Q
S
E
T
I
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417628
326
36606
G49
D
T
A
Y
I
Y
A
G
G
E
S
E
R
I
L
Frog
Xenopus laevis
Q9PTM5
367
40964
K94
A
E
V
Y
A
A
G
K
A
E
V
V
L
G
N
Zebra Danio
Brachydanio rerio
NP_001002369
323
36462
Q50
A
L
M
Y
N
D
G
Q
A
E
S
I
I
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
82.4
76.2
N.A.
77.3
80.3
N.A.
N.A.
68.8
23.7
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.1
84.8
80.8
N.A.
81.1
88.2
N.A.
N.A.
82.4
42.7
78.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
73.3
N.A.
66.6
20
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
N.A.
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
0
78
12
12
0
23
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
56
0
0
12
0
0
0
45
0
0
0
0
23
% D
% Glu:
56
12
0
0
0
0
0
0
0
56
0
12
0
56
0
% E
% Phe:
0
12
0
0
0
56
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
34
12
12
0
56
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
12
0
0
0
0
0
0
23
12
12
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
34
0
0
0
0
12
0
0
0
0
0
23
0
12
% L
% Met:
0
0
12
0
0
0
23
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
23
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
23
0
0
0
56
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
56
0
23
0
56
0
12
% S
% Thr:
0
12
0
56
0
0
0
0
0
0
12
0
0
0
34
% T
% Val:
0
0
23
0
0
0
23
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
45
0
12
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _