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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4B All Species: 18.79
Human Site: S224 Identified Species: 31.79
UniProt: O95155 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95155 NP_001099032.1 1302 146185 S224 R D E N P F A S L T A T S Q P
Chimpanzee Pan troglodytes XP_001161430 1302 146197 S224 R D E N P F A S L T A T S Q P
Rhesus Macaque Macaca mulatta XP_001101836 1302 146120 S224 R D E N P F A S L T A T S Q P
Dog Lupus familis XP_849824 1312 147260 A234 A T S Q P I A A A A R S P D R
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 S184 V I F L S S L S A Q F K Q N P
Rat Rattus norvegicus Q6P7A2 1066 122361 E77 R S F R T H Q E M C E Q L N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515124 1303 145844 S219 R D E N P F A S L T A T S Q P
Chicken Gallus gallus XP_417607 1324 149015 S240 R D E N P F A S L T A T S Q P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_919343 1183 134341 L194 D V I F L P S L A A E F Q K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609597 1217 138573 E219 L L N A T W N E Y G S G S I I
Honey Bee Apis mellifera XP_395681 1103 125977 I114 T T S S S T E I T T E Q I H A
Nematode Worm Caenorhab. elegans Q09349 980 113212
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 E49 T A A E I L S E G K E L L L S
Baker's Yeast Sacchar. cerevisiae P54860 961 109887
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 95.9 N.A. 88 21.6 N.A. 90.9 86.9 N.A. 73.6 N.A. 33.5 39.6 24.2 N.A.
Protein Similarity: 100 99.8 99.8 96.6 N.A. 89.3 38.7 N.A. 93.3 91.4 N.A. 82 N.A. 52.8 57.5 41.7 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 13.3 6.6 N.A. 100 100 N.A. 0 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 13.3 N.A. 100 100 N.A. 13.3 N.A. 20 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 0 43 8 22 15 36 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 36 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 36 8 0 0 8 22 0 0 29 0 0 0 0 % E
% Phe: 0 0 15 8 0 36 0 0 0 0 8 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 8 0 8 8 0 8 0 0 0 0 8 8 15 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % K
% Leu: 8 8 0 8 8 8 8 8 36 0 0 8 15 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 8 36 0 0 8 0 0 0 0 0 0 15 8 % N
% Pro: 0 0 0 0 43 8 0 0 0 0 0 0 8 0 43 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 0 15 15 36 0 % Q
% Arg: 43 0 0 8 0 0 0 0 0 0 8 0 0 0 8 % R
% Ser: 0 8 15 8 15 8 15 43 0 0 8 8 43 0 8 % S
% Thr: 15 15 0 0 15 8 0 0 8 43 0 36 0 0 0 % T
% Val: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _