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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4B All Species: 10.91
Human Site: S314 Identified Species: 18.46
UniProt: O95155 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95155 NP_001099032.1 1302 146185 S314 S T P L S P H S A A S G T A A
Chimpanzee Pan troglodytes XP_001161430 1302 146197 S314 S T P L S P H S A A S G T A A
Rhesus Macaque Macaca mulatta XP_001101836 1302 146120 S314 S T P L S P H S A A S G T A A
Dog Lupus familis XP_849824 1312 147260 G324 M A S G T A T G S Q P S S P R
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 S274 S L S S L G A S G G A S N W D
Rat Rattus norvegicus Q6P7A2 1066 122361 D167 L N L S A D R D A G E R H I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515124 1303 145844 P309 V V V S P H L P G G S P S G G
Chicken Gallus gallus XP_417607 1324 149015 L330 S I T V S S H L T A T S P S W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_919343 1183 134341 S284 S L S S L G A S A G G M A G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609597 1217 138573 G309 T G G A T A S G E T A A A A A
Honey Bee Apis mellifera XP_395681 1103 125977 V204 A S P L Q S P V T T F C R C D
Nematode Worm Caenorhab. elegans Q09349 980 113212 D81 K F V L L S Q D G S R R G L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 P139 M F G N S D K P S G G L D N R
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 D62 K P F E Y L N D C F R R N Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 95.9 N.A. 88 21.6 N.A. 90.9 86.9 N.A. 73.6 N.A. 33.5 39.6 24.2 N.A.
Protein Similarity: 100 99.8 99.8 96.6 N.A. 89.3 38.7 N.A. 93.3 91.4 N.A. 82 N.A. 52.8 57.5 41.7 N.A.
P-Site Identity: 100 100 100 0 N.A. 13.3 6.6 N.A. 6.6 26.6 N.A. 20 N.A. 13.3 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 20 N.A. 20 13.3 N.A. 13.3 46.6 N.A. 20 N.A. 33.3 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 8 15 15 0 36 29 15 8 15 29 29 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % C
% Asp: 0 0 0 0 0 15 0 22 0 0 0 0 8 0 22 % D
% Glu: 0 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % E
% Phe: 0 15 8 0 0 0 0 0 0 8 8 0 0 0 8 % F
% Gly: 0 8 15 8 0 15 0 15 22 36 15 22 8 15 8 % G
% His: 0 0 0 0 0 8 29 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 15 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 15 8 36 22 8 8 8 0 0 0 8 0 8 0 % L
% Met: 15 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 8 0 0 8 0 0 0 0 0 15 8 0 % N
% Pro: 0 8 29 0 8 22 8 15 0 0 8 8 8 8 0 % P
% Gln: 0 0 0 0 8 0 8 0 0 8 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 15 22 8 0 15 % R
% Ser: 43 8 22 29 36 22 8 36 15 8 29 22 15 8 8 % S
% Thr: 8 22 8 0 15 0 8 0 15 15 8 0 22 0 0 % T
% Val: 8 8 15 8 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _