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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4B All Species: 16.67
Human Site: S373 Identified Species: 28.21
UniProt: O95155 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95155 NP_001099032.1 1302 146185 S373 S S S R Q R P S S T G P P L P
Chimpanzee Pan troglodytes XP_001161430 1302 146197 S373 S S S R Q R P S S T G P P L P
Rhesus Macaque Macaca mulatta XP_001101836 1302 146120 S373 S S S R Q R P S S T G P P L P
Dog Lupus familis XP_849824 1312 147260 S383 S S L R Q R P S S L G P P S V
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 S333 Q L L S N I R S Q C I S H T A
Rat Rattus norvegicus Q6P7A2 1066 122361 H226 I Y V D Q N I H E Q L V D L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515124 1303 145844 S368 P Q A A P T G S S R Q T P T T
Chicken Gallus gallus XP_417607 1324 149015 A389 P P A M L L T A P R Q R P T T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_919343 1183 134341 S343 Q L L S N I R S Q C I S H A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609597 1217 138573 T368 Q T E C S R K T P L T Q P A L
Honey Bee Apis mellifera XP_395681 1103 125977 S263 R A Q C V Q Y S S L V L Q G L
Nematode Worm Caenorhab. elegans Q09349 980 113212 K140 K T L E S T R K A V F S V F V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 D198 D S D F D S L D S I L K E L Y
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 V121 I N Y I T G I V S N V N S Y T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 95.9 N.A. 88 21.6 N.A. 90.9 86.9 N.A. 73.6 N.A. 33.5 39.6 24.2 N.A.
Protein Similarity: 100 99.8 99.8 96.6 N.A. 89.3 38.7 N.A. 93.3 91.4 N.A. 82 N.A. 52.8 57.5 41.7 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 6.6 13.3 N.A. 20 6.6 N.A. 6.6 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 6.6 13.3 N.A. 26.6 20 N.A. 6.6 N.A. 26.6 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 8 0 0 0 8 8 0 0 0 0 15 15 % A
% Cys: 0 0 0 15 0 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 8 0 8 8 8 0 0 8 0 0 0 0 8 0 0 % D
% Glu: 0 0 8 8 0 0 0 0 8 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 0 0 0 0 0 8 8 0 0 0 29 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 15 0 0 % H
% Ile: 15 0 0 8 0 15 15 0 0 8 15 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 8 8 0 0 0 8 0 0 0 % K
% Leu: 0 15 29 0 8 8 8 0 0 22 15 8 0 36 15 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 15 8 0 0 0 8 0 8 0 0 0 % N
% Pro: 15 8 0 0 8 0 29 0 15 0 0 29 50 0 22 % P
% Gln: 22 8 8 0 36 8 0 0 15 8 15 8 8 0 0 % Q
% Arg: 8 0 0 29 0 36 22 0 0 15 0 8 0 0 0 % R
% Ser: 29 36 22 15 15 8 0 58 58 0 0 22 8 8 0 % S
% Thr: 0 15 0 0 8 15 8 8 0 22 8 8 0 22 22 % T
% Val: 0 0 8 0 8 0 0 8 0 8 15 8 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 8 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _