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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4B All Species: 22.73
Human Site: T1242 Identified Species: 38.46
UniProt: O95155 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95155 NP_001099032.1 1302 146185 T1242 P L M D T L M T D P V R L P S
Chimpanzee Pan troglodytes XP_001161430 1302 146197 T1242 P L M D T L M T D P V R L P S
Rhesus Macaque Macaca mulatta XP_001101836 1302 146120 T1242 P L M D T L M T D P V R L P S
Dog Lupus familis XP_849824 1312 147260 T1252 P L M D T L M T D P V R L P S
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 G1121 D P V R L P S G T V M D R S I
Rat Rattus norvegicus Q6P7A2 1066 122361 V1014 L P S S R V T V D G S T I A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515124 1303 145844 T1243 P L M D T L M T D P V R L P S
Chicken Gallus gallus XP_417607 1324 149015 T1264 P L M D T L M T D P V R L P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_919343 1183 134341 G1131 D P V Q L P S G N I M D R S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609597 1217 138573 V1165 V V L P S G T V M D R A I I T
Honey Bee Apis mellifera XP_395681 1103 125977 I1051 P V K L P S G I V M D K A V I
Nematode Worm Caenorhab. elegans Q09349 980 113212 G928 D P V K L P S G H V M D R A V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 R986 D N H D P F N R A H L T S D M
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 R909 A S K M N I D R S T I K A H L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 95.9 N.A. 88 21.6 N.A. 90.9 86.9 N.A. 73.6 N.A. 33.5 39.6 24.2 N.A.
Protein Similarity: 100 99.8 99.8 96.6 N.A. 89.3 38.7 N.A. 93.3 91.4 N.A. 82 N.A. 52.8 57.5 41.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 0 6.6 N.A. 100 100 N.A. 0 N.A. 0 6.6 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 20 N.A. 100 100 N.A. 20 N.A. 33.3 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 8 0 0 8 15 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 0 0 50 0 0 8 0 50 8 8 22 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 22 0 8 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 8 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 8 0 8 0 8 8 0 15 8 22 % I
% Lys: 0 0 15 8 0 0 0 0 0 0 0 15 0 0 0 % K
% Leu: 8 43 8 8 22 43 0 0 0 0 8 0 43 0 8 % L
% Met: 0 0 43 8 0 0 43 0 8 8 22 0 0 0 8 % M
% Asn: 0 8 0 0 8 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 50 29 0 8 15 22 0 0 0 43 0 0 0 43 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 0 15 0 0 8 43 22 0 8 % R
% Ser: 0 8 8 8 8 8 22 0 8 0 8 0 8 15 43 % S
% Thr: 0 0 0 0 43 0 15 43 8 8 0 15 0 0 8 % T
% Val: 8 15 22 0 0 8 0 15 8 15 43 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _