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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4B All Species: 9.09
Human Site: T375 Identified Species: 15.38
UniProt: O95155 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95155 NP_001099032.1 1302 146185 T375 S R Q R P S S T G P P L P P A
Chimpanzee Pan troglodytes XP_001161430 1302 146197 T375 S R Q R P S S T G P P L P P A
Rhesus Macaque Macaca mulatta XP_001101836 1302 146120 T375 S R Q R P S S T G P P L P P A
Dog Lupus familis XP_849824 1312 147260 L385 L R Q R P S S L G P P S V A A
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 C335 L S N I R S Q C I S H T A L V
Rat Rattus norvegicus Q6P7A2 1066 122361 Q228 V D Q N I H E Q L V D L M L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515124 1303 145844 R370 A A P T G S S R Q T P T T V G
Chicken Gallus gallus XP_417607 1324 149015 R391 A M L L T A P R Q R P T T M G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_919343 1183 134341 C345 L S N I R S Q C I S H A A L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609597 1217 138573 L370 E C S R K T P L T Q P A L Q L
Honey Bee Apis mellifera XP_395681 1103 125977 L265 Q C V Q Y S S L V L Q G L V G
Nematode Worm Caenorhab. elegans Q09349 980 113212 V142 L E S T R K A V F S V F V M I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 I200 D F D S L D S I L K E L Y E D
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 N123 Y I T G I V S N V N S Y T D F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 95.9 N.A. 88 21.6 N.A. 90.9 86.9 N.A. 73.6 N.A. 33.5 39.6 24.2 N.A.
Protein Similarity: 100 99.8 99.8 96.6 N.A. 89.3 38.7 N.A. 93.3 91.4 N.A. 82 N.A. 52.8 57.5 41.7 N.A.
P-Site Identity: 100 100 100 66.6 N.A. 6.6 13.3 N.A. 20 6.6 N.A. 6.6 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 6.6 13.3 N.A. 26.6 20 N.A. 6.6 N.A. 20 20 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.9 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 0 0 8 8 0 0 0 0 15 15 8 29 % A
% Cys: 0 15 0 0 0 0 0 15 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 8 0 0 0 0 8 0 0 8 8 % D
% Glu: 8 8 0 0 0 0 8 0 0 0 8 0 0 8 8 % E
% Phe: 0 8 0 0 0 0 0 0 8 0 0 8 0 0 8 % F
% Gly: 0 0 0 8 8 0 0 0 29 0 0 8 0 0 22 % G
% His: 0 0 0 0 0 8 0 0 0 0 15 0 0 0 0 % H
% Ile: 0 8 0 15 15 0 0 8 15 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 8 0 0 0 8 0 0 0 0 0 % K
% Leu: 29 0 8 8 8 0 0 22 15 8 0 36 15 22 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 8 15 0 % M
% Asn: 0 0 15 8 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 8 0 29 0 15 0 0 29 50 0 22 22 0 % P
% Gln: 8 0 36 8 0 0 15 8 15 8 8 0 0 8 0 % Q
% Arg: 0 29 0 36 22 0 0 15 0 8 0 0 0 0 0 % R
% Ser: 22 15 15 8 0 58 58 0 0 22 8 8 0 0 0 % S
% Thr: 0 0 8 15 8 8 0 22 8 8 0 22 22 0 0 % T
% Val: 8 0 8 0 0 8 0 8 15 8 8 0 15 15 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _