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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKAP
All Species:
15.45
Human Site:
S518
Identified Species:
30.91
UniProt:
O95163
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95163
NP_003631.2
1332
150254
S518
E
D
V
F
L
A
V
S
H
S
E
F
S
P
R
Chimpanzee
Pan troglodytes
XP_001142839
1332
150362
S518
E
D
I
F
L
A
V
S
H
S
E
F
S
P
R
Rhesus Macaque
Macaca mulatta
XP_001102913
1249
140865
L501
P
R
S
V
I
H
H
L
T
A
A
S
S
E
M
Dog
Lupus familis
XP_855277
1355
153048
S541
E
D
V
F
L
A
V
S
Y
S
P
S
S
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT37
1333
149565
S519
D
D
T
F
L
A
I
S
Y
S
H
S
S
S
Q
Rat
Rattus norvegicus
Q8VHU4
1331
149152
S517
G
D
A
F
L
A
I
S
H
S
H
S
S
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231708
627
69418
Frog
Xenopus laevis
Q2TAQ1
1170
132634
S453
C
V
Q
T
A
L
A
S
I
E
G
E
D
M
V
Zebra Danio
Brachydanio rerio
XP_689534
1322
148531
D548
L
R
S
D
I
E
V
D
G
H
V
I
S
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGK7
1252
142795
A509
N
G
L
V
N
A
V
A
V
A
P
Y
A
M
N
Honey Bee
Apis mellifera
XP_624197
1042
121409
W325
Y
N
M
H
H
F
L
W
L
D
E
T
S
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06706
1349
152972
V570
Q
P
T
L
I
T
I
V
E
V
Y
D
K
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
88
87
N.A.
80.9
80.9
N.A.
N.A.
31.8
54.4
58.6
N.A.
31.8
31.9
N.A.
N.A.
Protein Similarity:
100
99.4
90
92
N.A.
89
88.6
N.A.
N.A.
39.1
69.1
73.4
N.A.
50.3
49.4
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
73.3
N.A.
46.6
60
N.A.
N.A.
0
6.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
73.3
73.3
N.A.
N.A.
0
6.6
20
N.A.
46.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
50
9
9
0
17
9
0
9
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
42
0
9
0
0
0
9
0
9
0
9
9
0
0
% D
% Glu:
25
0
0
0
0
9
0
0
9
9
25
9
0
9
0
% E
% Phe:
0
0
0
42
0
9
0
0
0
0
0
17
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% G
% His:
0
0
0
9
9
9
9
0
25
9
17
0
0
0
0
% H
% Ile:
0
0
9
0
25
0
25
0
9
0
0
9
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
9
9
42
9
9
9
9
0
0
0
0
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
17
9
% M
% Asn:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
17
0
0
34
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
0
0
17
0
0
0
0
50
0
42
0
34
67
9
0
% S
% Thr:
0
0
17
9
0
9
0
0
9
0
0
9
0
0
0
% T
% Val:
0
9
17
17
0
0
42
9
9
9
9
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
17
0
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _