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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKBKAP All Species: 19.7
Human Site: S695 Identified Species: 39.39
UniProt: O95163 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95163 NP_003631.2 1332 150254 S695 L R K V E R G S R I V T V V P
Chimpanzee Pan troglodytes XP_001142839 1332 150362 S695 L R Q V E R G S R I V T V V P
Rhesus Macaque Macaca mulatta XP_001102913 1249 140865 V678 V P Q D T K L V L Q M P R G N
Dog Lupus familis XP_855277 1355 153048 S718 L R K V E R G S R I V T V V P
Cat Felis silvestris
Mouse Mus musculus Q7TT37 1333 149565 S696 L R K V E R G S R I V T V V P
Rat Rattus norvegicus Q8VHU4 1331 149152 S694 L R K V E R G S R I V T V V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231708 627 69418 T87 L E C V C V A T A A G D I L L
Frog Xenopus laevis Q2TAQ1 1170 132634 D630 L T E I K E E D V T K T M Y P
Zebra Danio Brachydanio rerio XP_689534 1322 148531 K725 L V L A Q L R K W L D G L R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGK7 1252 142795 N686 M S R K Q R I N L N I I F D H
Honey Bee Apis mellifera XP_624197 1042 121409 P502 G N L E C I Q P R A L S L Y I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06706 1349 152972 A747 Y P R I M V L A E V R K N I M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 88 87 N.A. 80.9 80.9 N.A. N.A. 31.8 54.4 58.6 N.A. 31.8 31.9 N.A. N.A.
Protein Similarity: 100 99.4 90 92 N.A. 89 88.6 N.A. N.A. 39.1 69.1 73.4 N.A. 50.3 49.4 N.A. N.A.
P-Site Identity: 100 93.3 0 100 N.A. 100 100 N.A. N.A. 13.3 20 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. N.A. 33.3 46.6 26.6 N.A. 40 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 9 9 17 0 0 0 0 0 % A
% Cys: 0 0 9 0 17 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 0 0 9 9 0 9 0 % D
% Glu: 0 9 9 9 42 9 9 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % F
% Gly: 9 0 0 0 0 0 42 0 0 0 9 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 17 0 9 9 0 0 42 9 9 9 9 9 % I
% Lys: 0 0 34 9 9 9 0 9 0 0 9 9 0 0 0 % K
% Leu: 67 0 17 0 0 9 17 0 17 9 9 0 17 9 9 % L
% Met: 9 0 0 0 9 0 0 0 0 0 9 0 9 0 9 % M
% Asn: 0 9 0 0 0 0 0 9 0 9 0 0 9 0 9 % N
% Pro: 0 17 0 0 0 0 0 9 0 0 0 9 0 0 50 % P
% Gln: 0 0 17 0 17 0 9 0 0 9 0 0 0 0 0 % Q
% Arg: 0 42 17 0 0 50 9 0 50 0 9 0 9 9 0 % R
% Ser: 0 9 0 0 0 0 0 42 0 0 0 9 0 0 0 % S
% Thr: 0 9 0 0 9 0 0 9 0 9 0 50 0 0 0 % T
% Val: 9 9 0 50 0 17 0 9 9 9 42 0 42 42 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _