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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKBKAP All Species: 28.18
Human Site: Y331 Identified Species: 56.36
UniProt: O95163 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95163 NP_003631.2 1332 150254 Y331 T V G N Y H W Y L K Q S L S F
Chimpanzee Pan troglodytes XP_001142839 1332 150362 Y331 T V G N Y H W Y L K Q S L S F
Rhesus Macaque Macaca mulatta XP_001102913 1249 140865 P320 L V S L M W D P V T P Y R L H
Dog Lupus familis XP_855277 1355 153048 Y354 T V G N Y H W Y L K Q S L P F
Cat Felis silvestris
Mouse Mus musculus Q7TT37 1333 149565 Y331 T V G N Y H W Y L K Q S L P F
Rat Rattus norvegicus Q8VHU4 1331 149152 Y331 T V G N Y H W Y L K Q S L P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231708 627 69418
Frog Xenopus laevis Q2TAQ1 1170 132634 E272 Q L S C A V N E V T F Q L E P
Zebra Danio Brachydanio rerio XP_689534 1322 148531 Y334 T V S N Y H W Y L K Q S L H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGK7 1252 142795 Y318 T I G N Y H W Y L K Q V L I F
Honey Bee Apis mellifera XP_624197 1042 121409 R144 E K N G L K H R E F L L P F K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06706 1349 152972 Y388 T S K N Y H W Y L K Q E L Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 88 87 N.A. 80.9 80.9 N.A. N.A. 31.8 54.4 58.6 N.A. 31.8 31.9 N.A. N.A.
Protein Similarity: 100 99.4 90 92 N.A. 89 88.6 N.A. N.A. 39.1 69.1 73.4 N.A. 50.3 49.4 N.A. N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. N.A. 0 6.6 86.6 N.A. 80 0 N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. N.A. 0 20 86.6 N.A. 86.6 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 9 9 0 0 9 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 59 % F
% Gly: 0 0 50 9 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 67 9 0 0 0 0 0 0 9 9 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 9 9 0 0 9 0 0 0 67 0 0 0 0 9 % K
% Leu: 9 9 0 9 9 0 0 0 67 0 9 9 75 9 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 67 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 9 0 9 25 9 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 67 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % R
% Ser: 0 9 25 0 0 0 0 0 0 0 0 50 0 17 0 % S
% Thr: 67 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % T
% Val: 0 59 0 0 0 9 0 0 17 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 9 67 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 0 67 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _