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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKAP
All Species:
26.67
Human Site:
Y917
Identified Species:
53.33
UniProt:
O95163
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95163
NP_003631.2
1332
150254
Y917
S
Q
K
D
P
K
E
Y
L
P
F
L
N
T
L
Chimpanzee
Pan troglodytes
XP_001142839
1332
150362
Y917
S
Q
K
D
P
K
E
Y
L
P
F
L
N
T
L
Rhesus Macaque
Macaca mulatta
XP_001102913
1249
140865
D854
N
Y
Q
R
F
T
I
D
K
Y
L
K
R
Y
E
Dog
Lupus familis
XP_855277
1355
153048
Y940
S
Q
K
D
P
K
E
Y
L
P
F
L
N
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT37
1333
149565
Y918
S
Q
K
D
P
K
E
Y
L
P
F
L
N
T
L
Rat
Rattus norvegicus
Q8VHU4
1331
149152
Y916
S
Q
K
D
P
K
E
Y
L
P
F
L
N
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231708
627
69418
R263
S
T
Q
E
K
P
N
R
H
D
V
V
F
L
E
Frog
Xenopus laevis
Q2TAQ1
1170
132634
S806
L
S
F
V
K
D
Q
S
L
Y
T
E
A
L
E
Zebra Danio
Brachydanio rerio
XP_689534
1322
148531
Y907
S
Q
K
D
P
K
E
Y
L
P
F
L
N
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGK7
1252
142795
K870
F
R
I
D
D
H
L
K
R
Y
T
S
A
L
S
Honey Bee
Apis mellifera
XP_624197
1042
121409
K678
S
A
L
E
H
I
A
K
E
S
N
R
F
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06706
1349
152972
Y951
S
Q
M
D
P
R
E
Y
L
P
F
L
Q
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
88
87
N.A.
80.9
80.9
N.A.
N.A.
31.8
54.4
58.6
N.A.
31.8
31.9
N.A.
N.A.
Protein Similarity:
100
99.4
90
92
N.A.
89
88.6
N.A.
N.A.
39.1
69.1
73.4
N.A.
50.3
49.4
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
93.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
26.6
13.3
93.3
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
0
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
67
9
9
0
9
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
17
0
0
59
0
9
0
0
9
0
9
34
% E
% Phe:
9
0
9
0
9
0
0
0
0
0
59
0
17
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
50
0
17
50
0
17
9
0
0
9
0
0
0
% K
% Leu:
9
0
9
0
0
0
9
0
67
0
9
59
0
25
59
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
0
9
0
50
9
0
% N
% Pro:
0
0
0
0
59
9
0
0
0
59
0
0
0
0
0
% P
% Gln:
0
59
17
0
0
0
9
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
0
9
0
9
0
9
9
0
0
9
9
0
0
% R
% Ser:
75
9
0
0
0
0
0
9
0
9
0
9
0
0
9
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
17
0
0
42
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
59
0
25
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _