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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCEL All Species: 10.91
Human Site: T222 Identified Species: 40
UniProt: O95171 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95171 NP_003834.3 688 77552 T222 K P G V Y T E T N R S A E R N
Chimpanzee Pan troglodytes XP_001141124 688 77657 T222 K P G V Y T E T N R S A E R N
Rhesus Macaque Macaca mulatta XP_001087679 688 77416 T222 K P G V Y T E T N R S A E R N
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9EQG3 652 72953 R206 R H A E R N I R T E D L D D I
Rat Rattus norvegicus NP_001101858 652 72833 T206 H A A R N I R T E D L D D I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085823 664 74335 V217 S S E K S K V V P R S P T V N
Zebra Danio Brachydanio rerio NP_001005304 572 63074 T126 S V K S L P R T S T T S T T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 94 N.A. N.A. 57.5 58.4 N.A. N.A. N.A. 30.9 23.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 96.6 N.A. N.A. 70.3 71.2 N.A. N.A. N.A. 49.1 42.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 0 6.6 N.A. N.A. N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 29 0 0 0 0 0 0 0 0 43 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 15 15 15 29 15 0 % D
% Glu: 0 0 15 15 0 0 43 0 15 15 0 0 43 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 15 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 15 0 0 0 0 0 0 15 29 % I
% Lys: 43 0 15 15 0 15 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 15 0 0 0 0 0 15 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 15 0 0 43 0 0 0 0 0 58 % N
% Pro: 0 43 0 0 0 15 0 0 15 0 0 15 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 15 15 0 29 15 0 58 0 0 0 43 0 % R
% Ser: 29 15 0 15 15 0 0 0 15 0 58 15 0 0 0 % S
% Thr: 0 0 0 0 0 43 0 72 15 15 15 0 29 15 15 % T
% Val: 0 15 0 43 0 0 15 15 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _