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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC5C
All Species:
4.55
Human Site:
S516
Identified Species:
9.09
UniProt:
O95185
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95185
NP_003719.2
931
103146
S516
L
L
E
N
E
A
L
S
L
K
N
Q
S
L
A
Chimpanzee
Pan troglodytes
XP_526636
931
103058
S516
L
L
E
N
E
A
L
S
L
K
N
Q
S
L
A
Rhesus Macaque
Macaca mulatta
XP_001106162
1131
123665
L715
L
H
L
R
S
A
S
L
G
S
Q
Q
L
L
G
Dog
Lupus familis
XP_861879
931
103199
H516
L
L
E
N
E
A
L
H
V
K
N
Q
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
O08747
931
103044
N516
L
L
E
N
E
A
L
N
L
K
N
Q
S
L
A
Rat
Rattus norvegicus
Q761X5
931
103116
N516
L
L
E
N
E
A
L
N
L
K
N
Q
S
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512141
852
93861
L479
P
Q
M
T
Q
S
L
L
D
E
T
L
N
M
K
Chicken
Gallus gallus
Q7T2Z5
931
102888
N516
L
L
E
N
E
T
L
N
V
K
N
Q
S
L
A
Frog
Xenopus laevis
Q8JGT4
943
105065
M528
M
N
A
R
N
K
N
M
S
M
Q
H
L
L
T
Zebra Danio
Brachydanio rerio
NP_001093454
948
105170
H537
D
T
I
G
R
R
T
H
T
Q
T
Q
T
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TU8
1072
116399
F640
A
D
T
S
N
S
T
F
D
M
N
G
K
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q26261
919
101607
R514
Q
I
D
S
N
G
A
R
L
S
L
S
K
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
54.7
97.2
N.A.
97
96.9
N.A.
59.4
92.6
62.4
77.6
N.A.
27.7
N.A.
28.4
N.A.
Protein Similarity:
100
99.8
65.1
98.7
N.A.
98.8
98.7
N.A.
69.1
96.4
76.3
86.9
N.A.
43.2
N.A.
45.5
N.A.
P-Site Identity:
100
100
26.6
86.6
N.A.
93.3
93.3
N.A.
6.6
80
6.6
13.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
100
100
N.A.
40
93.3
13.3
26.6
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
50
9
0
0
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
0
0
0
17
0
0
0
0
0
0
% D
% Glu:
0
0
50
0
50
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
0
0
9
0
0
9
0
0
17
% G
% His:
0
9
0
0
0
0
0
17
0
0
0
9
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
50
0
0
17
0
9
% K
% Leu:
59
50
9
0
0
0
59
17
42
0
9
9
17
84
0
% L
% Met:
9
0
9
0
0
0
0
9
0
17
0
0
0
9
9
% M
% Asn:
0
9
0
50
25
0
9
25
0
0
59
0
9
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
9
0
0
0
0
9
17
67
0
0
0
% Q
% Arg:
0
0
0
17
9
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
9
17
9
17
9
17
0
9
50
9
9
% S
% Thr:
0
9
9
9
0
9
17
0
9
0
17
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _