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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL2
All Species:
17.88
Human Site:
S21
Identified Species:
39.33
UniProt:
O95198
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95198
NP_009177.3
593
65975
S21
G
H
Q
K
P
L
D
S
K
D
D
N
T
E
K
Chimpanzee
Pan troglodytes
XP_517523
593
66157
S25
G
H
Q
K
P
L
D
S
K
D
D
N
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001100501
593
65972
S21
G
H
Q
K
P
L
D
S
K
D
D
N
T
E
K
Dog
Lupus familis
XP_532713
604
67348
S32
G
H
Q
K
P
L
D
S
K
D
D
N
T
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZP3
593
65964
S21
G
H
Q
K
P
L
D
S
K
D
E
N
P
E
K
Rat
Rattus norvegicus
Q8K430
640
69714
A45
E
R
A
R
P
R
Q
A
R
P
A
A
P
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420390
592
65925
D23
K
P
L
D
L
K
D
D
N
T
E
I
H
C
P
Frog
Xenopus laevis
Q6NRH0
564
63190
L22
I
L
N
T
M
N
S
L
R
K
S
Q
T
L
C
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
N26
M
N
A
L
R
K
S
N
T
L
C
D
I
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04652
1477
159964
A107
G
S
C
L
L
R
Y
A
S
Q
N
S
L
D
E
Honey Bee
Apis mellifera
XP_393674
1049
117222
A31
S
C
L
L
L
R
Y
A
S
Q
N
S
L
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
99.6
97.1
N.A.
98.8
44.8
N.A.
N.A.
92
40.8
40.8
N.A.
25.4
35.9
N.A.
N.A.
Protein Similarity:
100
98.1
99.8
97.1
N.A.
99.4
59.8
N.A.
N.A.
96.6
58.5
57.8
N.A.
32.4
45.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
6.6
N.A.
N.A.
6.6
6.6
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
N.A.
13.3
13.3
20
N.A.
40
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
28
0
0
10
10
0
0
0
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
10
0
0
10
10
% C
% Asp:
0
0
0
10
0
0
55
10
0
46
37
10
0
19
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
19
0
0
46
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
46
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
10
0
0
46
0
19
0
0
46
10
0
0
0
0
46
% K
% Leu:
0
10
19
28
28
46
0
10
0
10
0
0
19
10
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
10
0
0
10
0
10
10
0
19
46
0
0
0
% N
% Pro:
0
10
0
0
55
0
0
0
0
10
0
0
19
0
10
% P
% Gln:
0
0
46
0
0
0
10
0
0
19
0
10
0
0
0
% Q
% Arg:
0
10
0
10
10
28
0
0
19
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
19
46
19
0
10
19
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
10
10
0
0
46
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _