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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL2 All Species: 22.42
Human Site: T301 Identified Species: 49.33
UniProt: O95198 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95198 NP_009177.3 593 65975 T301 S V R T R L R T P M N L P K L
Chimpanzee Pan troglodytes XP_517523 593 66157 T305 S V R T R L R T P M N L P K L
Rhesus Macaque Macaca mulatta XP_001100501 593 65972 T301 S V R T R L R T P M N L P K L
Dog Lupus familis XP_532713 604 67348 T312 S V R T R L R T P M N L P K L
Cat Felis silvestris
Mouse Mus musculus Q8JZP3 593 65964 T301 S V R T R L R T P M N L P K L
Rat Rattus norvegicus Q8K430 640 69714 C335 S R T R P R R C E G A G P V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420390 592 65925 T300 S T R T K L R T P V S L P K L
Frog Xenopus laevis Q6NRH0 564 63190 G274 P R T R V R L G A N E V L L V
Zebra Danio Brachydanio rerio Q5U374 564 62914 G274 P R T Q A R L G A K E V L L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04652 1477 159964 M401 V P R K P V G M P K I L L V I
Honey Bee Apis mellifera XP_393674 1049 117222 Q323 T P R T K P R Q P R G L P K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 99.6 97.1 N.A. 98.8 44.8 N.A. N.A. 92 40.8 40.8 N.A. 25.4 35.9 N.A. N.A.
Protein Similarity: 100 98.1 99.8 97.1 N.A. 99.4 59.8 N.A. N.A. 96.6 58.5 57.8 N.A. 32.4 45.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 73.3 0 0 N.A. 20 46.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 93.3 13.3 13.3 N.A. 33.3 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 19 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 19 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 19 0 10 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % I
% Lys: 0 0 0 10 19 0 0 0 0 19 0 0 0 64 0 % K
% Leu: 0 0 0 0 0 55 19 0 0 0 0 73 28 19 64 % L
% Met: 0 0 0 0 0 0 0 10 0 46 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 46 0 0 0 0 % N
% Pro: 19 19 0 0 19 10 0 0 73 0 0 0 73 0 0 % P
% Gln: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 28 73 19 46 28 73 0 0 10 0 0 0 0 0 % R
% Ser: 64 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % S
% Thr: 10 10 28 64 0 0 0 55 0 0 0 0 0 0 0 % T
% Val: 10 46 0 0 10 10 0 0 0 10 0 19 0 19 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _