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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCBTB2
All Species:
14.85
Human Site:
S188
Identified Species:
36.3
UniProt:
O95199
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95199
NP_001259.1
551
60315
S188
S
G
Q
V
G
S
G
S
T
V
N
Q
P
I
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101036
537
58923
V182
T
G
C
L
Q
N
K
V
V
V
T
I
A
C
G
Dog
Lupus familis
XP_542564
415
44530
Y60
S
A
G
N
E
V
L
Y
T
T
V
N
D
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99LJ7
551
60145
S188
S
G
Q
V
G
S
G
S
T
A
N
Q
P
I
P
Rat
Rattus norvegicus
Q6P798
551
60104
S188
S
G
Q
V
G
S
G
S
T
A
N
Q
P
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514077
541
59269
R186
T
A
N
Q
P
I
P
R
R
V
T
S
C
L
Q
Chicken
Gallus gallus
XP_417055
566
62248
S204
S
G
Q
V
G
S
G
S
T
A
N
Q
P
I
P
Frog
Xenopus laevis
Q52KW8
513
55477
V158
A
H
S
L
L
I
T
V
E
G
K
L
W
S
W
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391873
535
59752
T180
M
K
V
N
S
T
L
T
D
K
R
V
V
C
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782246
535
58264
S180
S
T
P
R
K
V
V
S
V
L
G
G
K
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88.5
71.5
N.A.
95.2
94.9
N.A.
86.7
84.4
20.8
N.A.
N.A.
N.A.
42.2
N.A.
55.5
Protein Similarity:
100
N.A.
91.2
73.5
N.A.
97.2
97.4
N.A.
92.7
91.1
38.1
N.A.
N.A.
N.A.
62.9
N.A.
71.5
P-Site Identity:
100
N.A.
13.3
13.3
N.A.
93.3
93.3
N.A.
6.6
93.3
0
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
N.A.
33.3
13.3
N.A.
93.3
93.3
N.A.
20
93.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
0
0
0
0
0
30
0
0
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
20
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
10
0
40
0
40
0
0
10
10
10
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
10
0
40
20
% I
% Lys:
0
10
0
0
10
0
10
0
0
10
10
0
10
0
0
% K
% Leu:
0
0
0
20
10
0
20
0
0
10
0
10
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
20
0
10
0
0
0
0
40
10
0
0
0
% N
% Pro:
0
0
10
0
10
0
10
0
0
0
0
0
40
0
40
% P
% Gln:
0
0
40
10
10
0
0
0
0
0
0
40
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
10
10
0
10
0
0
10
0
% R
% Ser:
60
0
10
0
10
40
0
50
0
0
0
10
0
10
0
% S
% Thr:
20
10
0
0
0
10
10
10
50
10
20
0
0
0
0
% T
% Val:
0
0
10
40
0
20
10
20
20
30
10
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _