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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LETM1 All Species: 30.61
Human Site: S301 Identified Species: 56.11
UniProt: O95202 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95202 NP_036450.1 739 83354 S301 R E T G E R P S N E E I M R F
Chimpanzee Pan troglodytes XP_001171298 444 50543 D81 S Y R Q K I M D E L K Y Y Y N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545925 741 83362 S301 R E T G E R P S N E E I L R F
Cat Felis silvestris
Mouse Mus musculus Q9Z2I0 738 82970 S300 R E T G E R P S N E E I M R F
Rat Rattus norvegicus Q5XIN6 739 83041 S300 R E T G E R P S N E E I M R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516696 577 64046 T214 H L N Q E I P T S L L I L S R
Chicken Gallus gallus Q5ZK33 752 85831 S298 R E T G E R P S N E E I L R F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LY46 757 86828 S308 R D S G E I P S N E Q I I R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91927 1013 113562 S329 R N P T E P V S N D E I I K F
Honey Bee Apis mellifera XP_624231 764 87758 T265 R T S G A V A T N E E I M Q F
Nematode Worm Caenorhab. elegans NP_506381 784 88704 L269 S M G Q L R S L C R L M S I N
Sea Urchin Strong. purpuratus XP_781116 544 61879 P181 M G V P P S Q P E V I M V P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08179 573 64987 E210 L I T Y N T I E N A E K K Q K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 N.A. 85.8 N.A. 83.9 83.6 N.A. 55 73.5 N.A. 63.5 N.A. 30.3 34.1 35.2 20.4
Protein Similarity: 100 46.9 N.A. 91.3 N.A. 89.1 89 N.A. 62.2 83.9 N.A. 78.7 N.A. 46 56.6 56.6 38.5
P-Site Identity: 100 0 N.A. 93.3 N.A. 100 100 N.A. 20 93.3 N.A. 66.6 N.A. 46.6 53.3 6.6 0
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. 40 100 N.A. 93.3 N.A. 66.6 73.3 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 39 0 0 62 0 0 8 16 54 62 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62 % F
% Gly: 0 8 8 54 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 24 8 0 0 0 8 70 16 8 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 8 8 8 8 16 % K
% Leu: 8 8 0 0 8 0 0 8 0 16 16 0 24 0 0 % L
% Met: 8 8 0 0 0 0 8 0 0 0 0 16 31 0 0 % M
% Asn: 0 8 8 0 8 0 0 0 70 0 0 0 0 0 16 % N
% Pro: 0 0 8 8 8 8 54 8 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 24 0 0 8 0 0 0 8 0 0 16 0 % Q
% Arg: 62 0 8 0 0 47 0 0 0 8 0 0 0 47 8 % R
% Ser: 16 0 16 0 0 8 8 54 8 0 0 0 8 8 0 % S
% Thr: 0 8 47 8 0 8 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 8 8 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 8 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _