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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LETM1 All Species: 22.73
Human Site: S428 Identified Species: 41.67
UniProt: O95202 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95202 NP_036450.1 739 83354 S428 M Y L P D T L S P A D Q L K S
Chimpanzee Pan troglodytes XP_001171298 444 50543 R195 E T M T E M A R R N R A K M G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545925 741 83362 S428 M Y L P D T L S P A D Q L K S
Cat Felis silvestris
Mouse Mus musculus Q9Z2I0 738 82970 S427 M Y L P D T L S P A D Q L K S
Rat Rattus norvegicus Q5XIN6 739 83041 S427 M Y L P D T L S P A D Q L K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516696 577 64046 D328 S P S A R E P D P D L A K V P
Chicken Gallus gallus Q5ZK33 752 85831 S425 M Y L P D T L S P A D Q L K T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LY46 757 86828 S435 M F L P D T L S P A D Q L K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91927 1013 113562 I456 M L I S D D S I T T D K L K E
Honey Bee Apis mellifera XP_624231 764 87758 P392 L M V P E T I P M S D K L K A
Nematode Worm Caenorhab. elegans NP_506381 784 88704 A386 Q N L P D G L A E T T K Q K L
Sea Urchin Strong. purpuratus XP_781116 544 61879 K295 L T K E L K L K L Q M A K F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08179 573 64987 G324 S R G M K A Y G V S K E D L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 N.A. 85.8 N.A. 83.9 83.6 N.A. 55 73.5 N.A. 63.5 N.A. 30.3 34.1 35.2 20.4
Protein Similarity: 100 46.9 N.A. 91.3 N.A. 89.1 89 N.A. 62.2 83.9 N.A. 78.7 N.A. 46 56.6 56.6 38.5
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. 6.6 93.3 N.A. 86.6 N.A. 33.3 33.3 33.3 6.6
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 46.6 80 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 8 8 0 47 0 24 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 62 8 0 8 0 8 62 0 8 0 0 % D
% Glu: 8 0 0 8 16 8 0 0 8 0 0 8 0 0 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 0 8 0 8 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 8 8 0 8 0 0 8 24 24 70 0 % K
% Leu: 16 8 54 0 8 0 62 0 8 0 8 0 62 8 16 % L
% Met: 54 8 8 8 0 8 0 0 8 0 8 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 62 0 0 8 8 54 0 0 0 0 0 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 8 0 47 8 0 0 % Q
% Arg: 0 8 0 0 8 0 0 8 8 0 8 0 0 0 0 % R
% Ser: 16 0 8 8 0 0 8 47 0 16 0 0 0 0 31 % S
% Thr: 0 16 0 8 0 54 0 0 8 16 8 0 0 0 16 % T
% Val: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 39 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _