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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM1
All Species:
25.76
Human Site:
S549
Identified Species:
47.22
UniProt:
O95202
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95202
NP_036450.1
739
83354
S549
K
E
E
I
D
I
L
S
D
A
C
S
K
L
Q
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
L291
A
K
E
G
V
T
A
L
S
V
S
E
L
Q
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545925
741
83362
S550
K
E
E
I
D
I
L
S
N
A
C
S
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2I0
738
82970
S548
K
E
E
I
D
I
L
S
D
A
C
S
K
L
Q
Rat
Rattus norvegicus
Q5XIN6
739
83041
S548
K
E
E
I
D
I
L
S
D
A
C
S
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516696
577
64046
K424
V
E
E
S
K
A
S
K
R
L
T
K
R
V
N
Chicken
Gallus gallus
Q5ZK33
752
85831
S561
K
E
E
I
D
M
L
S
D
A
C
N
K
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
S564
K
E
E
I
D
M
L
S
D
A
C
T
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
S559
E
T
D
K
G
I
S
S
T
D
V
Q
L
L
S
Honey Bee
Apis mellifera
XP_624231
764
87758
N534
K
G
A
I
R
L
F
N
K
V
N
K
M
I
N
Nematode Worm
Caenorhab. elegans
NP_506381
784
88704
A486
T
E
A
K
E
P
A
A
K
P
S
E
A
K
E
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
Q391
L
R
F
Q
L
R
M
Q
L
R
T
L
M
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08179
573
64987
S420
D
V
S
E
S
K
S
S
A
A
E
T
E
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
N.A.
85.8
N.A.
83.9
83.6
N.A.
55
73.5
N.A.
63.5
N.A.
30.3
34.1
35.2
20.4
Protein Similarity:
100
46.9
N.A.
91.3
N.A.
89.1
89
N.A.
62.2
83.9
N.A.
78.7
N.A.
46
56.6
56.6
38.5
P-Site Identity:
100
6.6
N.A.
86.6
N.A.
100
93.3
N.A.
13.3
86.6
N.A.
80
N.A.
20
13.3
6.6
0
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
26.6
100
N.A.
100
N.A.
33.3
33.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
8
16
8
8
54
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% C
% Asp:
8
0
8
0
47
0
0
0
39
8
0
0
0
0
8
% D
% Glu:
8
62
62
8
8
0
0
0
0
0
8
16
8
0
16
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
54
0
39
0
0
0
0
0
0
0
8
0
% I
% Lys:
54
8
0
16
8
8
0
8
16
0
0
16
47
8
24
% K
% Leu:
8
0
0
0
8
8
47
8
8
8
0
8
16
54
0
% L
% Met:
0
0
0
0
0
16
8
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
8
8
0
0
16
% N
% Pro:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
0
8
0
8
24
% Q
% Arg:
0
8
0
0
8
8
0
0
8
8
0
0
8
0
0
% R
% Ser:
0
0
8
8
8
0
24
62
8
0
16
31
0
0
8
% S
% Thr:
8
8
0
0
0
8
0
0
8
0
16
16
0
0
0
% T
% Val:
8
8
0
0
8
0
0
0
0
16
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _