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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM1
All Species:
16.97
Human Site:
S624
Identified Species:
31.11
UniProt:
O95202
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95202
NP_036450.1
739
83354
S624
G
Q
I
D
G
L
I
S
Q
L
E
M
D
Q
Q
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
I365
G
E
A
P
K
T
D
I
L
V
E
L
P
T
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545925
741
83362
S625
G
Q
I
D
S
L
L
S
Q
L
E
M
D
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2I0
738
82970
T623
G
Q
I
D
G
L
I
T
Q
L
E
T
T
Q
Q
Rat
Rattus norvegicus
Q5XIN6
739
83041
T623
G
Q
I
D
G
L
I
T
Q
L
E
T
T
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516696
577
64046
A498
K
L
N
S
L
A
G
A
L
D
E
N
Q
D
G
Chicken
Gallus gallus
Q5ZK33
752
85831
N635
G
Q
I
D
K
I
I
N
E
L
E
T
N
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
T639
G
R
M
D
K
I
I
T
E
L
E
K
D
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
N638
S
Q
L
D
N
V
L
N
D
L
E
A
R
Q
H
Honey Bee
Apis mellifera
XP_624231
764
87758
K620
D
D
R
D
G
A
I
K
I
E
D
V
L
K
V
Nematode Worm
Caenorhab. elegans
NP_506381
784
88704
D574
E
D
V
D
S
M
V
D
K
L
E
D
E
K
R
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
E465
S
R
A
L
Y
L
P
E
H
L
S
T
G
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08179
573
64987
T494
E
K
E
N
A
E
P
T
D
S
A
E
A
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
N.A.
85.8
N.A.
83.9
83.6
N.A.
55
73.5
N.A.
63.5
N.A.
30.3
34.1
35.2
20.4
Protein Similarity:
100
46.9
N.A.
91.3
N.A.
89.1
89
N.A.
62.2
83.9
N.A.
78.7
N.A.
46
56.6
56.6
38.5
P-Site Identity:
100
13.3
N.A.
80
N.A.
80
80
N.A.
6.6
53.3
N.A.
40
N.A.
33.3
20
20
20
P-Site Similarity:
100
33.3
N.A.
93.3
N.A.
86.6
86.6
N.A.
13.3
86.6
N.A.
80
N.A.
60
40
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
16
0
8
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
70
0
0
8
8
16
8
8
8
24
16
0
% D
% Glu:
16
8
8
0
0
8
0
8
16
8
77
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
54
0
0
0
31
0
8
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
39
0
0
16
47
8
8
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
24
0
0
8
8
0
0
8
0
24
16
% K
% Leu:
0
8
8
8
8
39
16
0
16
70
0
8
8
0
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
16
0
0
8
% M
% Asn:
0
0
8
8
8
0
0
16
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
8
0
0
16
0
0
0
0
0
8
0
0
% P
% Gln:
0
47
0
0
0
0
0
0
31
0
0
0
8
47
31
% Q
% Arg:
0
16
8
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
16
0
0
8
16
0
0
16
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
31
0
0
0
31
16
16
0
% T
% Val:
0
0
8
0
0
8
8
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _