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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LETM1 All Species: 2.73
Human Site: S64 Identified Species: 5
UniProt: O95202 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95202 NP_036450.1 739 83354 S64 P I H P V Y T S S R G D H L G
Chimpanzee Pan troglodytes XP_001171298 444 50543
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545925 741 83362 A64 P V H P I H L A F R A N P R G
Cat Felis silvestris
Mouse Mus musculus Q9Z2I0 738 82970 F64 A H P V Y L C F K G E P L S C
Rat Rattus norvegicus Q5XIN6 739 83041 F64 A N P V Y L Y F K S E P L S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516696 577 64046 M23 V F I V V P F M E F L L P V A
Chicken Gallus gallus Q5ZK33 752 85831 C67 S K K D H Y C C W T K G L E R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LY46 757 86828 S68 V Q Y L D N S S V L Q R R L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91927 1013 113562 L64 V L E L S R S L G T Y R R F Q
Honey Bee Apis mellifera XP_624231 764 87758 T64 L S Y V Q F R T F Y I T P I W
Nematode Worm Caenorhab. elegans NP_506381 784 88704 A71 V Q K Q D E E A Q K V L S L M
Sea Urchin Strong. purpuratus XP_781116 544 61879
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08179 573 64987 Y19 T R R Q A S L Y F V K N Q G P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 N.A. 85.8 N.A. 83.9 83.6 N.A. 55 73.5 N.A. 63.5 N.A. 30.3 34.1 35.2 20.4
Protein Similarity: 100 46.9 N.A. 91.3 N.A. 89.1 89 N.A. 62.2 83.9 N.A. 78.7 N.A. 46 56.6 56.6 38.5
P-Site Identity: 100 0 N.A. 33.3 N.A. 0 0 N.A. 6.6 6.6 N.A. 13.3 N.A. 0 0 6.6 0
P-Site Similarity: 100 0 N.A. 66.6 N.A. 0 0 N.A. 13.3 6.6 N.A. 26.6 N.A. 13.3 26.6 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 8 0 0 16 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 16 8 0 0 0 0 0 0 16 % C
% Asp: 0 0 0 8 16 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 8 0 0 8 8 0 8 0 16 0 0 8 0 % E
% Phe: 0 8 0 0 0 8 8 16 24 8 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 8 8 8 0 8 16 % G
% His: 0 8 16 0 8 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 8 0 8 0 0 0 0 0 8 0 0 8 0 % I
% Lys: 0 8 16 0 0 0 0 0 16 8 16 0 0 0 0 % K
% Leu: 8 8 0 16 0 16 16 8 0 8 8 16 24 24 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 16 0 0 0 % N
% Pro: 16 0 16 16 0 8 0 0 0 0 0 16 24 0 8 % P
% Gln: 0 16 0 16 8 0 0 0 8 0 8 0 8 0 8 % Q
% Arg: 0 8 8 0 0 8 8 0 0 16 0 16 16 8 8 % R
% Ser: 8 8 0 0 8 8 16 16 8 8 0 0 8 16 8 % S
% Thr: 8 0 0 0 0 0 8 8 0 16 0 8 0 0 0 % T
% Val: 31 8 0 31 16 0 0 0 8 8 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % W
% Tyr: 0 0 16 0 16 16 8 8 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _