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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LETM1 All Species: 1.52
Human Site: S84 Identified Species: 2.78
UniProt: O95202 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95202 NP_036450.1 739 83354 S84 P E C L R I V S R A P W T S T
Chimpanzee Pan troglodytes XP_001171298 444 50543
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545925 741 83362 A84 P E R V C V A A G V P W T P T
Cat Felis silvestris
Mouse Mus musculus Q9Z2I0 738 82970 A83 P E C Q G T A A R T T W T P A
Rat Rattus norvegicus Q5XIN6 739 83041 A83 P E C Q G T V A R A A W T P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516696 577 64046 P39 K L F P N M L P S T F E T Q S
Chicken Gallus gallus Q5ZK33 752 85831 S83 Y F T L M S S S G S W T P L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LY46 757 86828 H94 P D P A L P V H S R S T Y H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91927 1013 113562 F85 Y D Y S G Y G F R H L H T S R
Honey Bee Apis mellifera XP_624231 764 87758 V80 G Q E S S S K V E D T I K N I
Nematode Worm Caenorhab. elegans NP_506381 784 88704 V87 S D K D V A T V K P P L K D R
Sea Urchin Strong. purpuratus XP_781116 544 61879
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08179 573 64987 S35 L I A S T I P S C H W P L R A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 N.A. 85.8 N.A. 83.9 83.6 N.A. 55 73.5 N.A. 63.5 N.A. 30.3 34.1 35.2 20.4
Protein Similarity: 100 46.9 N.A. 91.3 N.A. 89.1 89 N.A. 62.2 83.9 N.A. 78.7 N.A. 46 56.6 56.6 38.5
P-Site Identity: 100 0 N.A. 40 N.A. 40 53.3 N.A. 6.6 13.3 N.A. 13.3 N.A. 20 0 6.6 0
P-Site Similarity: 100 0 N.A. 60 N.A. 46.6 60 N.A. 26.6 20 N.A. 20 N.A. 26.6 13.3 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 16 24 0 16 8 0 0 0 31 % A
% Cys: 0 0 24 0 8 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 24 0 8 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 31 8 0 0 0 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 8 8 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 0 24 0 8 0 16 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 16 0 8 0 8 0 % H
% Ile: 0 8 0 0 0 16 0 0 0 0 0 8 0 0 8 % I
% Lys: 8 0 8 0 0 0 8 0 8 0 0 0 16 0 0 % K
% Leu: 8 8 0 16 8 0 8 0 0 0 8 8 8 8 0 % L
% Met: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 39 0 8 8 0 8 8 8 0 8 24 8 8 24 0 % P
% Gln: 0 8 0 16 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 8 0 0 0 31 8 0 0 0 8 24 % R
% Ser: 8 0 0 24 8 16 8 24 16 8 8 0 0 16 8 % S
% Thr: 0 0 8 0 8 16 8 0 0 16 16 16 47 0 16 % T
% Val: 0 0 0 8 8 8 24 16 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 16 31 0 0 0 % W
% Tyr: 16 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _