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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZRANB2
All Species:
13.64
Human Site:
S258
Identified Species:
27.27
UniProt:
O95218
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95218
NP_005446.2
330
37404
S258
S
R
G
S
K
S
R
S
S
S
R
S
H
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099181
257
29208
D186
D
L
S
K
Y
N
L
D
A
S
E
E
E
D
S
Dog
Lupus familis
XP_547334
330
37367
S258
S
R
G
S
K
S
R
S
S
S
R
S
H
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R020
330
37332
S258
S
R
G
S
K
S
R
S
S
S
R
S
H
R
G
Rat
Rattus norvegicus
Q6AXY7
542
63914
R468
S
K
E
K
S
N
K
R
S
R
S
G
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519157
313
35396
R242
S
K
S
R
S
S
S
R
S
H
R
G
S
S
S
Chicken
Gallus gallus
Q5ZLX5
334
37844
S258
S
R
S
R
G
S
K
S
R
S
S
S
R
S
Y
Frog
Xenopus laevis
NP_001084142
337
37788
K258
H
S
R
S
P
G
S
K
S
R
S
S
S
R
S
Zebra Danio
Brachydanio rerio
NP_998572
198
22647
F127
S
D
G
E
Y
D
E
F
G
R
I
K
K
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392865
185
21530
R114
Y
G
G
G
Y
N
D
R
G
V
V
E
Y
K
E
Nematode Worm
Caenorhab. elegans
Q10021
208
23961
S136
V
R
E
S
R
R
R
S
E
S
R
S
P
S
P
Sea Urchin
Strong. purpuratus
XP_785599
345
39775
R256
R
S
R
S
R
D
R
R
R
S
K
D
G
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
77.8
99.6
N.A.
96.9
21.7
N.A.
91.5
94.3
75.9
46
N.A.
N.A.
33.6
26.6
52.1
Protein Similarity:
100
N.A.
77.8
99.6
N.A.
97.5
33.2
N.A.
92.1
96.7
82.7
51.8
N.A.
N.A.
42.1
36.6
64.6
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
20
N.A.
26.6
40
26.6
13.3
N.A.
N.A.
6.6
46.6
26.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
46.6
N.A.
33.3
46.6
26.6
20
N.A.
N.A.
26.6
53.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
17
9
9
0
0
0
9
0
9
0
% D
% Glu:
0
0
17
9
0
0
9
0
9
0
9
17
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
9
42
9
9
9
0
0
17
0
0
17
9
0
34
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
25
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
17
0
17
25
0
17
9
0
0
9
9
9
17
0
% K
% Leu:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
42
17
17
17
9
42
34
17
25
42
0
9
42
0
% R
% Ser:
59
17
25
50
17
42
17
42
50
59
25
50
25
25
34
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
25
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _