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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNX4
All Species:
25.45
Human Site:
S227
Identified Species:
56
UniProt:
O95219
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95219
NP_003785.1
450
51909
S227
F
T
D
L
K
H
Y
S
D
E
L
Q
S
V
I
Chimpanzee
Pan troglodytes
XP_001169563
481
54978
S227
F
T
D
L
K
H
Y
S
D
E
L
Q
S
V
I
Rhesus Macaque
Macaca mulatta
XP_001114118
449
51860
S226
F
T
D
L
K
H
Y
S
D
E
L
Q
S
V
I
Dog
Lupus familis
XP_535771
403
47195
L201
R
A
R
V
A
D
R
L
Y
G
V
Y
K
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ2
450
51759
S227
F
T
E
L
R
H
Y
S
D
E
L
Q
S
V
I
Rat
Rattus norvegicus
NP_001121022
450
51923
S227
F
T
E
L
R
Q
Y
S
D
E
L
Q
S
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422107
435
50106
S212
F
T
E
L
K
H
Y
S
D
E
L
Q
S
V
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q566W7
430
49451
Y217
K
M
G
E
S
V
K
Y
V
T
G
G
Y
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397464
392
45495
L195
G
I
E
L
Q
N
N
L
C
N
L
L
R
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785792
405
46821
R205
K
S
L
S
A
S
F
R
L
K
K
P
N
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGV1
493
55348
S253
F
I
E
I
K
E
K
S
D
K
L
D
E
D
L
Conservation
Percent
Protein Identity:
100
90.8
97.1
87.7
N.A.
94
94
N.A.
N.A.
83.1
N.A.
21.7
N.A.
N.A.
43.7
N.A.
43.1
Protein Similarity:
100
92
98
88.8
N.A.
96.6
96.4
N.A.
N.A.
88.2
N.A.
42.6
N.A.
N.A.
62.4
N.A.
63.5
P-Site Identity:
100
100
100
6.6
N.A.
86.6
80
N.A.
N.A.
93.3
N.A.
0
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
93.3
N.A.
N.A.
100
N.A.
6.6
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
19
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
28
0
0
10
0
0
64
0
0
10
0
10
0
% D
% Glu:
0
0
46
10
0
10
0
0
0
55
0
0
10
0
0
% E
% Phe:
64
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
10
10
10
0
0
0
% G
% His:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
55
% I
% Lys:
19
0
0
0
46
0
19
0
0
19
10
0
10
10
0
% K
% Leu:
0
0
10
64
0
0
0
19
10
0
73
10
0
0
19
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
55
0
0
10
% Q
% Arg:
10
0
10
0
19
0
10
10
0
0
0
0
10
10
10
% R
% Ser:
0
10
0
10
10
10
0
64
0
0
0
0
55
0
0
% S
% Thr:
0
55
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
10
0
10
0
0
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
55
10
10
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _