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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNX4 All Species: 24.85
Human Site: S61 Identified Species: 54.67
UniProt: O95219 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95219 NP_003785.1 450 51909 S61 W L K K I E I S V S E A E K R
Chimpanzee Pan troglodytes XP_001169563 481 54978 S61 W L K K I E I S V S E A E K R
Rhesus Macaque Macaca mulatta XP_001114118 449 51860 S61 W L K K I E I S V S E A E K R
Dog Lupus familis XP_535771 403 47195 D44 L I E T R S V D H T D G Q S V
Cat Felis silvestris
Mouse Mus musculus Q91YJ2 450 51759 S61 W L K K I E I S V S E A E K R
Rat Rattus norvegicus NP_001121022 450 51923 S61 W L K K I E I S V S E A E K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422107 435 50106 T45 L A K K M E I T V S E A E K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q566W7 430 49451 S47 N P G E K D L S L P N G T P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397464 392 45495 I45 E F Y T V Y L I E T K V T D P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785792 405 46821 E53 V V E I N V T E Q E K R T G N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGV1 493 55348 S74 E I L D C T V S D P H K E N D
Conservation
Percent
Protein Identity: 100 90.8 97.1 87.7 N.A. 94 94 N.A. N.A. 83.1 N.A. 21.7 N.A. N.A. 43.7 N.A. 43.1
Protein Similarity: 100 92 98 88.8 N.A. 96.6 96.4 N.A. N.A. 88.2 N.A. 42.6 N.A. N.A. 62.4 N.A. 63.5
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. N.A. 73.3 N.A. 6.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 40 N.A. 100 100 N.A. N.A. 86.6 N.A. 33.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 21.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 39.3
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 55 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 0 10 10 0 10 0 0 10 10 % D
% Glu: 19 0 19 10 0 55 0 10 10 10 55 0 64 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 19 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 0 19 0 10 46 0 55 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 55 55 10 0 0 0 0 0 19 10 0 55 0 % K
% Leu: 19 46 10 0 0 0 19 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 0 0 0 10 0 0 10 10 % N
% Pro: 0 10 0 0 0 0 0 0 0 19 0 0 0 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 55 % R
% Ser: 0 0 0 0 0 10 0 64 0 55 0 0 0 10 0 % S
% Thr: 0 0 0 19 0 10 10 10 0 19 0 0 28 0 0 % T
% Val: 10 10 0 0 10 10 19 0 55 0 0 10 0 0 19 % V
% Trp: 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _