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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF20A
All Species:
20.91
Human Site:
S226
Identified Species:
38.33
UniProt:
O95235
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95235
NP_005724.1
890
100278
S226
Q
E
E
M
K
K
L
S
L
L
N
G
G
L
Q
Chimpanzee
Pan troglodytes
XP_517952
890
100260
S226
Q
E
E
M
K
K
L
S
L
L
N
G
G
L
Q
Rhesus Macaque
Macaca mulatta
XP_001107307
922
103446
S226
Q
E
E
M
K
K
L
S
L
L
N
G
G
L
Q
Dog
Lupus familis
XP_531919
451
50384
Cat
Felis silvestris
Mouse
Mus musculus
P97329
887
99858
S225
Q
E
E
M
K
K
L
S
L
L
I
G
G
L
Q
Rat
Rattus norvegicus
NP_001101896
888
99998
S225
Q
E
E
I
K
K
L
S
L
L
I
G
G
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012801
881
99178
S225
Q
E
E
T
K
K
Q
S
M
L
R
G
G
V
W
Frog
Xenopus laevis
NP_001088540
884
100897
L224
E
E
L
R
K
V
S
L
L
S
N
L
R
E
E
Zebra Danio
Brachydanio rerio
NP_001154942
921
103544
A240
A
E
E
M
R
R
D
A
L
L
K
E
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V877
628
71368
L39
R
P
N
K
K
M
R
L
F
D
N
I
Q
E
S
Honey Bee
Apis mellifera
XP_624103
1180
137226
L244
L
E
I
K
T
K
L
L
T
F
A
S
V
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
G109
G
K
T
F
T
M
E
G
V
R
S
Q
P
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53086
805
91072
E217
G
I
I
F
L
A
M
E
E
L
F
N
K
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.5
47
N.A.
86.8
87.3
N.A.
N.A.
70.2
63
44.8
N.A.
20.8
20.7
N.A.
20.5
Protein Similarity:
100
99.8
95.3
49.3
N.A.
92.2
92.8
N.A.
N.A.
81.8
78
63.6
N.A.
35
38.3
N.A.
38.8
P-Site Identity:
100
100
100
0
N.A.
93.3
86.6
N.A.
N.A.
60
26.6
33.3
N.A.
13.3
20
N.A.
0
P-Site Similarity:
100
100
100
0
N.A.
93.3
93.3
N.A.
N.A.
73.3
40
53.3
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
0
0
8
8
0
% D
% Glu:
8
70
54
0
0
0
8
8
8
0
0
8
0
31
8
% E
% Phe:
0
0
0
16
0
0
0
0
8
8
8
0
0
0
0
% F
% Gly:
16
0
0
0
0
0
0
8
0
0
0
47
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
8
0
0
0
0
0
0
16
8
0
8
0
% I
% Lys:
0
8
0
16
62
54
0
0
0
0
8
0
8
0
8
% K
% Leu:
8
0
8
0
8
0
47
24
54
62
0
8
0
39
8
% L
% Met:
0
0
0
39
0
16
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
39
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
47
0
0
0
0
0
8
0
0
0
0
8
8
0
39
% Q
% Arg:
8
0
0
8
8
8
8
0
0
8
8
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
8
47
0
8
8
8
0
0
16
% S
% Thr:
0
0
8
8
16
0
0
0
8
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
8
0
0
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _