KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF20A
All Species:
18.48
Human Site:
S274
Identified Species:
33.89
UniProt:
O95235
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95235
NP_005724.1
890
100278
S274
I
S
Q
C
T
S
S
S
Q
L
D
E
T
S
H
Chimpanzee
Pan troglodytes
XP_517952
890
100260
S274
I
S
Q
C
T
S
N
S
Q
L
D
E
T
S
H
Rhesus Macaque
Macaca mulatta
XP_001107307
922
103446
S274
I
S
Q
C
T
S
S
S
Q
L
D
E
T
S
H
Dog
Lupus familis
XP_531919
451
50384
Cat
Felis silvestris
Mouse
Mus musculus
P97329
887
99858
S273
T
S
Q
F
T
S
S
S
Q
L
D
E
T
S
Q
Rat
Rattus norvegicus
NP_001101896
888
99998
S273
T
S
Q
F
T
S
S
S
Q
L
D
E
T
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012801
881
99178
S273
S
S
S
S
Q
F
T
S
H
S
D
I
S
Q
A
Frog
Xenopus laevis
NP_001088540
884
100897
Q272
F
V
N
Q
T
S
S
Q
L
E
E
T
C
S
R
Zebra Danio
Brachydanio rerio
NP_001154942
921
103544
L288
V
C
L
E
A
N
G
L
C
L
S
G
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V877
628
71368
G87
D
S
S
N
V
E
T
G
P
Q
V
F
L
R
L
Honey Bee
Apis mellifera
XP_624103
1180
137226
N292
V
S
F
A
E
I
Y
N
E
I
V
Y
D
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
L157
Y
N
E
E
V
K
D
L
L
G
K
D
Q
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53086
805
91072
T265
R
L
V
I
R
E
D
T
Q
N
H
I
K
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.5
47
N.A.
86.8
87.3
N.A.
N.A.
70.2
63
44.8
N.A.
20.8
20.7
N.A.
20.5
Protein Similarity:
100
99.8
95.3
49.3
N.A.
92.2
92.8
N.A.
N.A.
81.8
78
63.6
N.A.
35
38.3
N.A.
38.8
P-Site Identity:
100
93.3
100
0
N.A.
80
80
N.A.
N.A.
20
26.6
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
0
N.A.
80
80
N.A.
N.A.
33.3
33.3
20
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
8
0
24
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
0
0
16
0
0
0
47
8
8
0
8
% D
% Glu:
0
0
8
16
8
16
0
0
8
8
8
39
0
8
0
% E
% Phe:
8
0
8
16
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
8
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
31
% H
% Ile:
24
0
0
8
0
8
0
0
0
8
0
16
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
8
8
0
0
0
0
16
16
47
0
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
8
8
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
39
8
8
0
0
8
47
8
0
0
8
16
16
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
8
62
16
8
0
47
39
47
0
8
8
0
8
47
0
% S
% Thr:
16
0
0
0
47
0
16
8
0
0
0
8
39
0
0
% T
% Val:
16
8
8
0
16
0
0
0
0
0
16
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _