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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF20A
All Species:
10.91
Human Site:
T253
Identified Species:
20
UniProt:
O95235
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95235
NP_005724.1
890
100278
T253
Y
I
E
S
R
I
G
T
S
T
S
F
D
S
G
Chimpanzee
Pan troglodytes
XP_517952
890
100260
T253
Y
I
E
S
R
I
G
T
S
T
S
F
D
S
G
Rhesus Macaque
Macaca mulatta
XP_001107307
922
103446
T253
Y
I
E
S
R
I
G
T
S
T
S
F
D
S
G
Dog
Lupus familis
XP_531919
451
50384
Cat
Felis silvestris
Mouse
Mus musculus
P97329
887
99858
A252
H
T
E
S
R
I
G
A
S
N
S
F
D
S
G
Rat
Rattus norvegicus
NP_001101896
888
99998
A252
H
A
E
S
R
I
G
A
S
N
S
F
D
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012801
881
99178
A252
S
A
E
S
Q
L
Q
A
T
N
S
G
S
F
D
Frog
Xenopus laevis
NP_001088540
884
100897
S251
S
R
A
G
T
S
I
S
F
D
S
G
I
G
G
Zebra Danio
Brachydanio rerio
NP_001154942
921
103544
A267
S
G
I
S
G
L
S
A
T
S
H
I
A
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V877
628
71368
S66
S
E
Y
K
Y
Q
S
S
E
A
T
E
G
A
S
Honey Bee
Apis mellifera
XP_624103
1180
137226
N271
L
L
Q
E
E
S
P
N
R
P
S
Q
C
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
E136
G
H
I
A
K
E
Q
E
N
V
R
F
L
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53086
805
91072
E244
S
Y
L
E
I
Y
N
E
R
I
R
D
L
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.5
47
N.A.
86.8
87.3
N.A.
N.A.
70.2
63
44.8
N.A.
20.8
20.7
N.A.
20.5
Protein Similarity:
100
99.8
95.3
49.3
N.A.
92.2
92.8
N.A.
N.A.
81.8
78
63.6
N.A.
35
38.3
N.A.
38.8
P-Site Identity:
100
100
100
0
N.A.
73.3
73.3
N.A.
N.A.
20
13.3
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
0
N.A.
80
80
N.A.
N.A.
40
20
33.3
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
0
0
0
31
0
8
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
8
39
0
16
% D
% Glu:
0
8
47
16
8
8
0
16
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
47
0
8
0
% F
% Gly:
8
8
0
8
8
0
39
0
0
0
0
16
8
8
47
% G
% His:
16
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
24
16
0
8
39
8
0
0
8
0
8
8
8
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
8
8
0
0
16
0
0
0
0
0
0
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
8
24
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
8
16
0
0
0
0
8
0
0
8
% Q
% Arg:
0
8
0
0
39
0
0
0
16
0
16
0
0
0
8
% R
% Ser:
39
0
0
54
0
16
16
16
39
8
62
0
8
39
8
% S
% Thr:
0
8
0
0
8
0
0
24
16
24
8
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
8
8
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _