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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDEF
All Species:
30
Human Site:
S264
Identified Species:
60
UniProt:
O95238
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95238
NP_036523.1
335
37518
S264
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Chimpanzee
Pan troglodytes
XP_001171692
335
37471
S264
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Rhesus Macaque
Macaca mulatta
XP_001116514
343
38470
S272
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Dog
Lupus familis
XP_538872
759
84050
S688
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTP3
325
36338
S254
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Rat
Rattus norvegicus
NP_001103000
325
36319
S254
E
L
L
L
K
P
H
S
Y
G
R
F
I
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10157
479
54522
T384
Q
F
L
L
E
L
L
T
D
K
S
C
Q
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
S364
V
A
L
L
D
D
P
S
N
A
H
F
I
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29775
518
57695
V445
E
L
L
A
S
P
Q
V
N
G
T
A
I
R
W
Honey Bee
Apis mellifera
XP_396511
603
66106
V530
E
L
L
Q
S
P
G
V
H
G
S
C
I
R
W
Nematode Worm
Caenorhab. elegans
NP_001123137
437
49748
Q364
E
L
L
D
Q
P
K
Q
Y
S
A
C
V
R
W
Sea Urchin
Strong. purpuratus
NP_999699
363
40750
S292
E
L
L
L
Q
P
N
S
Y
S
Y
C
I
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.9
42
N.A.
85.9
86.8
N.A.
N.A.
22.5
N.A.
21.8
N.A.
32
28.1
24.9
29.2
Protein Similarity:
100
99
85.4
42.9
N.A.
90.4
91.9
N.A.
N.A.
35.7
N.A.
35.2
N.A.
42.2
38.3
39.8
46
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
40
N.A.
53.3
53.3
46.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
40
N.A.
40
N.A.
53.3
60
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
0
0
9
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% C
% Asp:
0
0
0
9
9
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
84
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
59
0
0
9
% F
% Gly:
0
0
0
0
0
0
9
0
0
67
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
84
0
0
% I
% Lys:
0
0
0
0
50
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
0
84
100
75
0
9
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
84
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
17
0
9
9
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
50
0
0
84
0
% R
% Ser:
0
0
0
0
17
0
0
67
0
17
17
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
17
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
92
% W
% Tyr:
0
0
0
0
0
0
0
0
67
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _