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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 17.58
Human Site: S1048 Identified Species: 25.78
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S1048 I E D L K Y C S E H S V N E H
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1041 I E D L K Y C S E H S V N E H
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1048 I E D L K Y C S E H S V N E H
Dog Lupus familis XP_549061 1234 139874 S1050 I E D L K Y Y S E H S V N E P
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S1050 V G E L Q Y Y S E P S V A E Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 E1200 I E T L N K Y E D K I Q Q L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 R1042 R Q T V A K P R A P T P E M N
Frog Xenopus laevis Q91784 1226 138905 L1050 A K S A A V I L E D L L S E S
Zebra Danio Brachydanio rerio Q58G59 1363 154819 L1153 V G W L E A A L E R Q Q L E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L611 W K F S S M S L P T P P G G D
Honey Bee Apis mellifera XP_395595 1064 123475 E891 S I E E Y E N E D N N K L R E
Nematode Worm Caenorhab. elegans P46873 699 78760 R526 H G E F E L D R L D Y L D T I
Sea Urchin Strong. purpuratus P46872 699 78679 I526 R E Q E R M D I E E K Y S S L
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 G871 Q Y M F N S L G D A R C Q L W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 T862 M F N S L A E T R C Q L W E K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E755 R D L Q N R C E R V V E L E I
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 100 100 86.6 N.A. 46.6 20 N.A. N.A. 0 13.3 20 N.A. 0 0 0 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 66.6 26.6 N.A. N.A. 26.6 33.3 33.3 N.A. 6.6 26.6 26.6 26.6
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 0 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 6.6 N.A. N.A. 33.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 13 13 7 0 7 7 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 25 0 0 7 0 7 0 0 0 % C
% Asp: 0 7 25 0 0 0 13 0 19 13 0 0 7 0 7 % D
% Glu: 0 38 19 13 13 7 7 19 50 7 0 7 7 57 13 % E
% Phe: 0 7 7 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 0 0 7 0 0 0 0 7 7 0 % G
% His: 7 0 0 0 0 0 0 0 0 25 0 0 0 0 19 % H
% Ile: 32 7 0 0 0 0 7 7 0 0 7 0 0 0 13 % I
% Lys: 0 13 0 0 25 13 0 0 0 7 7 7 0 0 7 % K
% Leu: 0 0 7 44 7 7 7 19 7 0 7 19 19 13 7 % L
% Met: 7 0 7 0 0 13 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 7 0 19 0 7 0 0 7 7 0 25 0 7 % N
% Pro: 0 0 0 0 0 0 7 0 7 13 7 13 0 0 7 % P
% Gln: 7 7 7 7 7 0 0 0 0 0 13 13 13 0 7 % Q
% Arg: 19 0 0 0 7 7 0 13 13 7 7 0 0 7 0 % R
% Ser: 7 0 7 13 7 7 7 32 0 0 32 0 13 7 7 % S
% Thr: 0 0 13 0 0 0 0 7 0 7 7 0 0 7 0 % T
% Val: 13 0 0 7 0 7 0 0 0 7 7 32 0 0 0 % V
% Trp: 7 0 7 0 0 0 0 0 0 0 0 0 7 0 7 % W
% Tyr: 0 7 0 0 7 32 19 0 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _