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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 26.97
Human Site: S1219 Identified Species: 39.56
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S1219 R A L A S N T S F F S G C S P
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1214 R A L A S N T S F F S G C S P
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1221 R A L A S N T S F F S G C S P
Dog Lupus familis XP_549061 1234 139874 S1221 R A L A S N T S F F S G C S P
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S1218 R A L A S N T S F F S G C S P
Rat Rattus norvegicus Q7M6Z5 1394 158861 R1381 S S L G A G V R S V T A D S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S1212 R M L S S N T S F F S G C T P
Frog Xenopus laevis Q91784 1226 138905 S1214 V L C N S N T S F F S G C S A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 P1348 R S S L N T A P L Y S S S A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 A772 R L P A K K P A S A Y P K A R
Honey Bee Apis mellifera XP_395595 1064 123475 S1052 T I V Y Y I E S G Q N Y K E L
Nematode Worm Caenorhab. elegans P46873 699 78760 A687 L Y E R A Q S A K R P P R L A
Sea Urchin Strong. purpuratus P46872 699 78679 Q687 P K T G K K K Q A S M A S S I
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 I1034 P W R L S E L I R H S D E T V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 S1023 S D E T L L K S K P R L K A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 P916 A T L Q Q N P P E N K R S S W
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 80 66.6 13.3 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. N.A. 93.3 66.6 40 N.A. 26.6 20 20 6.6
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 32 0 38 13 0 7 13 7 7 0 13 0 19 13 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 44 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 0 7 7 0 0 % D
% Glu: 0 0 13 0 0 7 7 0 7 0 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 44 44 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 7 0 0 7 0 0 44 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 7 0 7 0 0 0 0 0 0 13 % I
% Lys: 0 7 0 0 13 13 13 0 13 0 7 0 19 0 0 % K
% Leu: 7 13 50 13 7 7 7 0 7 0 0 7 0 7 19 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 7 7 50 0 0 0 7 7 0 0 0 0 % N
% Pro: 13 0 7 0 0 0 13 13 0 7 7 13 0 0 38 % P
% Gln: 0 0 0 7 7 7 0 7 0 7 0 0 0 0 0 % Q
% Arg: 50 0 7 7 0 0 0 7 7 7 7 7 7 0 7 % R
% Ser: 13 13 7 7 50 0 7 57 13 7 57 7 19 57 0 % S
% Thr: 7 7 7 7 0 7 44 0 0 0 7 0 0 13 0 % T
% Val: 7 0 7 0 0 0 7 0 0 7 0 0 0 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 7 0 7 7 0 0 0 0 7 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _