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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 15.15
Human Site: S548 Identified Species: 22.22
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S548 R K M T Q N D S Q L Q P I Q Y
Chimpanzee Pan troglodytes XP_518055 1227 139177 N548 R K M T Q N D N Q L Q P I Q F
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S548 R K M T Q N D S Q L Q P I Q Y
Dog Lupus familis XP_549061 1234 139874 S549 R K M T Q N D S Q L Q P I H F
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 N549 K K M T Q N D N Q L Q P I Q F
Rat Rattus norvegicus Q7M6Z5 1394 158861 L696 S Y L G N G D L K M E S L Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S554 K K M I Q N D S Q L E P I Q S
Frog Xenopus laevis Q91784 1226 138905 R551 K K M A Q N D R Q L E P I Q S
Zebra Danio Brachydanio rerio Q58G59 1363 154819 K653 I N V T W T K K D I A I P Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 H224 N E H S S R S H A I F M I K I
Honey Bee Apis mellifera XP_395595 1064 123475 L503 E I C S P D S L D D F D E K Q
Nematode Worm Caenorhab. elegans P46873 699 78760 Y139 H C S Y L E I Y N E E V R D L
Sea Urchin Strong. purpuratus P46872 699 78679 R139 A K E Q E N V R F L V R V S Y
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 G475 I C S V K T D G L K R S L H S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 H471 D G L K R S L H S I E S S N Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 S368 N Y I V N L E S E V Q V W R G
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 86.6 100 86.6 N.A. 80 13.3 N.A. N.A. 73.3 66.6 13.3 N.A. 6.6 0 0 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 46.6 N.A. N.A. 86.6 80 26.6 N.A. 33.3 20 6.6 40
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 26.6 N.A. N.A. 40 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 0 7 0 7 0 0 0 0 % A
% Cys: 0 13 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 57 0 13 7 0 7 0 7 0 % D
% Glu: 7 7 7 0 7 7 7 0 7 7 32 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 13 0 0 0 19 % F
% Gly: 0 7 0 7 0 7 0 7 0 0 0 0 0 0 13 % G
% His: 7 0 7 0 0 0 0 13 0 0 0 0 0 13 0 % H
% Ile: 13 7 7 7 0 0 7 0 0 19 0 7 50 0 7 % I
% Lys: 19 50 0 7 7 0 7 7 7 7 0 0 0 13 0 % K
% Leu: 0 0 13 0 7 7 7 13 7 50 0 0 13 0 7 % L
% Met: 0 0 44 0 0 0 0 0 0 7 0 7 0 0 0 % M
% Asn: 13 7 0 0 13 50 0 13 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 44 7 0 0 % P
% Gln: 0 0 0 7 44 0 0 0 44 0 38 0 0 50 7 % Q
% Arg: 25 0 0 0 7 7 0 13 0 0 7 7 7 7 0 % R
% Ser: 7 0 13 13 7 7 13 32 7 0 0 19 7 7 19 % S
% Thr: 0 0 0 38 0 13 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 13 0 0 7 0 0 7 7 13 7 0 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 13 0 7 0 0 0 7 0 0 0 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _