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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4A
All Species:
26.06
Human Site:
S595
Identified Species:
38.22
UniProt:
O95239
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95239
NP_036442.3
1232
139881
S595
D
A
N
Q
A
K
L
S
E
R
R
R
K
R
L
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
S588
D
V
N
Q
A
K
L
S
E
H
R
H
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S595
D
V
N
Q
A
K
L
S
E
R
R
R
K
R
L
Dog
Lupus familis
XP_549061
1234
139874
S596
D
V
N
Q
A
K
L
S
E
R
R
R
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S596
D
A
N
Q
A
K
L
S
E
R
R
R
K
R
L
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
N732
K
M
R
E
L
T
I
N
I
R
M
K
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S601
D
V
N
Q
A
K
L
S
E
R
R
R
K
R
L
Frog
Xenopus laevis
Q91784
1226
138905
S598
D
N
N
Q
A
K
L
S
E
R
R
R
K
R
L
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
E694
T
S
N
S
S
I
G
E
S
S
V
W
E
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
K259
A
G
S
E
R
Q
S
K
T
G
A
S
A
E
R
Honey Bee
Apis mellifera
XP_395595
1064
123475
I538
L
A
I
K
E
S
L
I
C
Q
L
L
K
N
S
Nematode Worm
Caenorhab. elegans
P46873
699
78760
V174
V
A
G
L
S
M
H
V
C
H
D
V
P
A
C
Sea Urchin
Strong. purpuratus
P46872
699
78679
V174
E
V
K
E
R
P
D
V
G
V
Y
V
K
D
L
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
H511
E
V
A
K
E
W
E
H
T
L
L
Q
N
T
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199593
1035
116715
S506
E
H
K
L
L
Q
N
S
M
D
K
E
L
Y
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
R403
K
S
A
S
T
T
A
R
P
S
T
P
S
R
L
Conservation
Percent
Protein Identity:
100
93.1
96.4
94.8
N.A.
87
27
N.A.
N.A.
74.5
68.5
25.8
N.A.
26.9
36.8
27.1
27.3
Protein Similarity:
100
95.6
97.2
97
N.A.
92.7
47.6
N.A.
N.A.
85.9
82.1
45.1
N.A.
41.4
56.3
38.4
39.3
P-Site Identity:
100
73.3
93.3
93.3
N.A.
100
13.3
N.A.
N.A.
93.3
93.3
6.6
N.A.
0
20
6.6
13.3
P-Site Similarity:
100
73.3
93.3
93.3
N.A.
100
46.6
N.A.
N.A.
93.3
93.3
33.3
N.A.
20
33.3
13.3
26.6
Percent
Protein Identity:
33.2
N.A.
N.A.
32.7
N.A.
26.7
Protein Similarity:
51
N.A.
N.A.
51
N.A.
44.5
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
13
0
44
0
7
0
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
7
% C
% Asp:
44
0
0
0
0
0
7
0
0
7
7
0
0
13
0
% D
% Glu:
19
0
0
19
13
0
7
7
44
0
0
7
13
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
7
0
7
7
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
7
7
0
13
0
7
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
7
7
0
0
0
0
0
0
% I
% Lys:
13
0
13
13
0
44
0
7
0
0
7
7
57
0
0
% K
% Leu:
7
0
0
13
13
0
50
0
0
7
13
7
7
7
63
% L
% Met:
0
7
0
0
0
7
0
0
7
0
7
0
0
0
7
% M
% Asn:
0
7
50
0
0
0
7
7
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
7
0
0
7
0
0
7
7
0
0
% P
% Gln:
0
0
0
44
0
13
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
0
7
0
13
0
0
7
0
44
44
38
0
44
7
% R
% Ser:
0
13
7
13
13
7
7
50
7
13
0
7
7
7
7
% S
% Thr:
7
0
0
0
7
13
0
0
13
0
7
0
0
7
0
% T
% Val:
7
38
0
0
0
0
0
13
0
7
7
13
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _