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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 23.64
Human Site: S822 Identified Species: 34.67
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S822 S I T K Q I E S L E T E M E F
Chimpanzee Pan troglodytes XP_518055 1227 139177 S815 C I T K Q I E S L E T E M E L
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S822 S I T K Q I E S L E T E M E F
Dog Lupus familis XP_549061 1234 139874 S823 S I T K Q I E S L E T E M E L
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S823 S I A K Q I E S L E T E L E L
Rat Rattus norvegicus Q7M6Z5 1394 158861 A989 T D S L K I S A R L N L L D Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S826 S L S K Q I E S L E T E M E L
Frog Xenopus laevis Q91784 1226 138905 L824 V T K Q I E S L E T E M E L R
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E915 G S V V S L E E Q Q K I E E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 T412 S D S L Q V S T I E Q P V E D
Honey Bee Apis mellifera XP_395595 1064 123475 I692 M W H N K Q E I V F K R K M E
Nematode Worm Caenorhab. elegans P46873 699 78760 I327 Y A N R A K N I K N K P T I N
Sea Urchin Strong. purpuratus P46872 699 78679 D327 G P A E Y N Y D E T I S T L R
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 K671 K E L L Q L R K E G R R N E Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 G662 L L Q L R K E G R K S E Y E R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 K556 L D E K E K K K A E K M A K M
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 86.6 100 93.3 N.A. 80 6.6 N.A. N.A. 80 0 13.3 N.A. 26.6 6.6 0 0
P-Site Similarity: 100 86.6 100 93.3 N.A. 86.6 46.6 N.A. N.A. 93.3 6.6 26.6 N.A. 60 20 6.6 6.6
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 13.3 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 26.6 N.A. N.A. 46.6 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 13 0 7 0 0 7 7 0 0 0 7 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 0 0 7 0 0 0 0 0 7 7 % D
% Glu: 0 7 7 7 7 7 57 7 19 50 7 44 13 63 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 13 % F
% Gly: 13 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 32 0 0 7 44 0 13 7 0 7 7 0 7 0 % I
% Lys: 7 0 7 44 13 19 7 13 7 7 25 0 7 7 0 % K
% Leu: 13 13 7 25 0 13 0 7 38 7 0 7 13 13 25 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 13 32 7 7 % M
% Asn: 0 0 7 7 0 7 7 0 0 7 7 0 7 0 7 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 13 0 0 0 % P
% Gln: 0 0 7 7 50 7 0 0 7 7 7 0 0 0 13 % Q
% Arg: 0 0 0 7 7 0 7 0 13 0 7 13 0 0 19 % R
% Ser: 38 7 19 0 7 0 19 38 0 0 7 7 0 0 0 % S
% Thr: 7 7 25 0 0 0 0 7 0 13 38 0 13 0 0 % T
% Val: 7 0 7 7 0 7 0 0 7 0 0 0 7 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 0 7 0 0 0 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _