KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4A
All Species:
27.88
Human Site:
S877
Identified Species:
40.89
UniProt:
O95239
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95239
NP_036442.3
1232
139881
S877
L
I
G
E
L
V
S
S
K
I
Q
V
S
K
L
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
S870
L
I
G
E
L
V
S
S
K
I
H
V
T
K
L
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S877
L
I
G
E
L
V
S
S
K
I
Q
V
S
K
L
Dog
Lupus familis
XP_549061
1234
139874
S878
L
I
G
E
L
V
S
S
K
I
Q
V
S
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S878
L
V
G
E
L
V
S
S
K
I
L
V
S
K
L
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
G1044
V
D
E
K
L
R
H
G
R
V
L
S
P
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S881
L
L
G
E
L
V
S
S
K
V
Q
E
S
K
L
Frog
Xenopus laevis
Q91784
1226
138905
S879
L
I
T
E
L
V
S
S
K
V
A
G
S
K
L
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
K970
E
R
S
G
L
E
S
K
K
L
R
S
S
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
V467
A
E
L
E
G
Q
L
V
R
G
G
K
N
L
L
Honey Bee
Apis mellifera
XP_395595
1064
123475
T747
E
I
E
I
L
I
S
T
I
D
A
E
Y
S
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
E382
E
E
R
K
K
L
R
E
E
F
E
E
A
M
N
Sea Urchin
Strong. purpuratus
P46872
699
78679
E382
G
E
G
L
D
D
D
E
E
S
G
S
E
E
S
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
S726
A
R
D
N
S
A
I
S
N
G
N
G
A
N
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199593
1035
116715
G717
E
H
S
A
G
T
N
G
F
G
T
N
G
Q
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
E611
E
D
I
K
A
L
R
E
K
L
V
E
T
Q
G
Conservation
Percent
Protein Identity:
100
93.1
96.4
94.8
N.A.
87
27
N.A.
N.A.
74.5
68.5
25.8
N.A.
26.9
36.8
27.1
27.3
Protein Similarity:
100
95.6
97.2
97
N.A.
92.7
47.6
N.A.
N.A.
85.9
82.1
45.1
N.A.
41.4
56.3
38.4
39.3
P-Site Identity:
100
86.6
100
100
N.A.
86.6
13.3
N.A.
N.A.
80
73.3
26.6
N.A.
13.3
26.6
0
6.6
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
40
N.A.
N.A.
93.3
80
46.6
N.A.
26.6
40
33.3
20
Percent
Protein Identity:
33.2
N.A.
N.A.
32.7
N.A.
26.7
Protein Similarity:
51
N.A.
N.A.
51
N.A.
44.5
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
7
7
0
0
0
0
13
0
13
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
7
0
7
7
7
0
0
7
0
0
0
0
0
% D
% Glu:
32
19
13
50
0
7
0
19
13
0
7
25
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
7
0
44
7
13
0
0
13
0
19
13
13
7
0
13
% G
% His:
0
7
0
0
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
0
38
7
7
0
7
7
0
7
32
0
0
0
0
0
% I
% Lys:
0
0
0
19
7
0
0
7
57
0
0
7
0
50
0
% K
% Leu:
44
7
7
7
63
13
7
0
0
13
13
0
0
7
57
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
7
0
0
7
0
7
0
7
7
7
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
25
0
0
19
0
% Q
% Arg:
0
13
7
0
0
7
13
0
13
0
7
0
0
0
0
% R
% Ser:
0
0
13
0
7
0
57
50
0
7
0
19
44
7
7
% S
% Thr:
0
0
7
0
0
7
0
7
0
0
7
0
13
0
7
% T
% Val:
7
7
0
0
0
44
0
7
0
19
7
32
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _