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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 25.76
Human Site: S887 Identified Species: 37.78
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S887 Q V S K L E S S L K Q S K T S
Chimpanzee Pan troglodytes XP_518055 1227 139177 S880 H V T K L E N S L R Q S K A S
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S887 Q V S K L E S S L K Q S K T S
Dog Lupus familis XP_549061 1234 139874 S888 Q V S K L E S S L K Q N K A S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S888 L V S K L E S S L N Q S K A S
Rat Rattus norvegicus Q7M6Z5 1394 158861 L1054 L S P K E E H L L F Q L E E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S891 Q E S K L E S S L Q Q S K T N
Frog Xenopus laevis Q91784 1226 138905 S889 A G S K L E S S V K Q N R A H
Zebra Danio Brachydanio rerio Q58G59 1363 154819 Q980 R S S Q A L S Q D L L T L S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 Y477 G K N L L D T Y S E R Q I E L
Honey Bee Apis mellifera XP_395595 1064 123475 L757 A E Y S L E K L M Q D R A S L
Nematode Worm Caenorhab. elegans P46873 699 78760 R392 E E A M N D L R G E Y E R E Q
Sea Urchin Strong. purpuratus P46872 699 78679 E392 G S E E S G D E E A G E G G V
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 N736 N G A N G Q S N E K S L Q R W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 K727 T N G Q T N E K S L Q R W L D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 R621 V E T Q G F V R Q A E L S S F
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 66.6 100 86.6 N.A. 80 26.6 N.A. N.A. 80 53.3 20 N.A. 6.6 13.3 0 0
P-Site Similarity: 100 86.6 100 93.3 N.A. 80 33.3 N.A. N.A. 93.3 73.3 46.6 N.A. 40 33.3 33.3 6.6
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 40 N.A. N.A. 13.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 7 0 0 0 0 13 0 0 7 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 7 0 7 0 7 0 0 0 7 % D
% Glu: 7 25 7 7 7 57 7 7 13 13 7 13 7 19 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 7 % F
% Gly: 13 13 7 0 13 7 0 0 7 0 7 0 7 7 7 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 7 0 50 0 0 7 7 0 32 0 0 38 0 0 % K
% Leu: 13 0 0 7 57 7 7 13 44 13 7 19 7 7 13 % L
% Met: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 7 7 7 7 7 7 7 7 0 7 0 13 0 0 7 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 25 0 0 19 0 7 0 7 7 13 57 7 7 0 7 % Q
% Arg: 7 0 0 0 0 0 0 13 0 7 7 13 13 7 0 % R
% Ser: 0 19 44 7 7 0 50 44 13 0 7 32 7 19 38 % S
% Thr: 7 0 13 0 7 0 7 0 0 0 0 7 0 19 0 % T
% Val: 7 32 0 0 0 0 7 0 7 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % W
% Tyr: 0 0 7 0 0 0 0 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _