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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 22.42
Human Site: S951 Identified Species: 32.89
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S951 A E K Q L E E S V S E K E Q Q
Chimpanzee Pan troglodytes XP_518055 1227 139177 S944 A E K Q L E K S A S E K E Q Q
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S951 A E K Q L E E S V S E K E Q Q
Dog Lupus familis XP_549061 1234 139874 S952 A E K Q L E E S V N E K E Q Q
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S952 T E K Q L E E S V S E K E Q Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 V1120 L F K Y F N K V I N L R E A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S955 P G K G V E D S L S E Q E K Q
Frog Xenopus laevis Q91784 1226 138905 E953 S V P V T I E E L P A E E I T
Zebra Danio Brachydanio rerio Q58G59 1363 154819 A1073 A I E Y K N E A I T Q R Q R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 K532 E V E L K K R K L S K C Y A K
Honey Bee Apis mellifera XP_395595 1064 123475 S812 E S D Q E N R S H L R W Q K I
Nematode Worm Caenorhab. elegans P46873 699 78760 E447 D Q F I G G E E A G N T Q L K
Sea Urchin Strong. purpuratus P46872 699 78679 R447 E D R N T V H R E L Q R R E S
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 P792 A S K G L S P P R G K N G F A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 G783 K G L S P P R G K N G F A R A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 K676 E V K A L L A K S L S D K S A
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 86.6 100 93.3 N.A. 93.3 13.3 N.A. N.A. 46.6 13.3 20 N.A. 6.6 13.3 6.6 0
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 46.6 N.A. N.A. 80 33.3 73.3 N.A. 40 26.6 26.6 33.3
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 20 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 26.6 N.A. N.A. 13.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 0 0 7 0 0 7 7 13 0 7 0 7 13 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 7 7 7 0 0 0 7 0 0 0 0 7 0 0 0 % D
% Glu: 25 32 13 0 7 38 44 13 7 0 38 7 50 7 7 % E
% Phe: 0 7 7 0 7 0 0 0 0 0 0 7 0 7 0 % F
% Gly: 0 13 0 13 7 7 0 7 0 13 7 0 7 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 7 0 0 13 0 0 0 0 7 7 % I
% Lys: 7 0 57 0 13 7 13 13 7 0 13 32 7 13 13 % K
% Leu: 7 0 7 7 44 7 0 0 19 19 7 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 19 0 0 0 19 7 7 0 0 0 % N
% Pro: 7 0 7 0 7 7 7 7 0 7 0 0 0 0 0 % P
% Gln: 0 7 0 38 0 0 0 0 0 0 13 7 19 32 44 % Q
% Arg: 0 0 7 0 0 0 19 7 7 0 7 19 7 13 0 % R
% Ser: 7 13 0 7 0 7 0 44 7 38 7 0 0 7 7 % S
% Thr: 7 0 0 0 13 0 0 0 0 7 0 7 0 0 7 % T
% Val: 0 19 0 7 7 7 0 7 25 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 13 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _