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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4A
All Species:
21.82
Human Site:
T500
Identified Species:
32
UniProt:
O95239
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95239
NP_036442.3
1232
139881
T500
E
Q
E
A
Q
V
E
T
S
P
E
T
S
R
S
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
T500
G
Q
E
A
Q
V
E
T
S
P
E
T
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
T500
E
Q
E
A
Q
V
E
T
S
P
E
T
N
R
S
Dog
Lupus familis
XP_549061
1234
139874
T501
E
P
E
A
Q
V
E
T
S
P
E
T
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S501
E
A
D
T
Q
V
Q
S
S
P
D
T
S
R
S
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
E526
G
H
A
V
S
L
K
E
A
Q
K
V
N
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
T506
D
A
A
G
E
A
E
T
G
Q
V
T
K
R
S
Frog
Xenopus laevis
Q91784
1226
138905
E503
A
S
F
P
V
P
E
E
D
S
G
E
K
R
S
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
S604
D
V
G
A
S
V
D
S
S
S
Y
S
E
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
V182
V
R
E
R
G
S
G
V
Y
V
P
N
L
H
A
Honey Bee
Apis mellifera
XP_395595
1064
123475
Q461
I
L
D
I
Q
N
D
Q
K
K
T
S
E
E
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
M97
G
S
G
K
T
F
S
M
Q
G
I
E
T
I
P
Sea Urchin
Strong. purpuratus
P46872
699
78679
G97
N
G
T
I
F
A
Y
G
Q
T
G
T
G
K
T
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
R431
E
V
Q
V
L
K
E
R
I
A
W
L
E
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199593
1035
116715
C429
E
T
A
N
E
E
L
C
R
E
L
H
E
Y
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
R326
S
T
L
R
F
G
M
R
A
K
S
I
K
N
K
Conservation
Percent
Protein Identity:
100
93.1
96.4
94.8
N.A.
87
27
N.A.
N.A.
74.5
68.5
25.8
N.A.
26.9
36.8
27.1
27.3
Protein Similarity:
100
95.6
97.2
97
N.A.
92.7
47.6
N.A.
N.A.
85.9
82.1
45.1
N.A.
41.4
56.3
38.4
39.3
P-Site Identity:
100
93.3
93.3
93.3
N.A.
60
6.6
N.A.
N.A.
33.3
20
20
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
86.6
40
N.A.
N.A.
46.6
20
60
N.A.
20
26.6
6.6
20
Percent
Protein Identity:
33.2
N.A.
N.A.
32.7
N.A.
26.7
Protein Similarity:
51
N.A.
N.A.
51
N.A.
44.5
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
19
32
0
13
0
0
13
7
0
0
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
13
0
13
0
0
0
13
0
7
0
7
0
0
0
0
% D
% Glu:
38
0
32
0
13
7
44
13
0
7
25
13
25
7
0
% E
% Phe:
0
0
7
0
13
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
7
13
7
7
7
7
7
7
7
13
0
7
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
0
% H
% Ile:
7
0
0
13
0
0
0
0
7
0
7
7
0
7
0
% I
% Lys:
0
0
0
7
0
7
7
0
7
13
7
0
19
7
7
% K
% Leu:
0
7
7
0
7
7
7
0
0
0
7
7
7
0
13
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
7
0
0
0
0
0
7
13
7
0
% N
% Pro:
0
7
0
7
0
7
0
0
0
32
7
0
0
0
7
% P
% Gln:
0
19
7
0
38
0
7
7
13
13
0
0
0
7
0
% Q
% Arg:
0
7
0
13
0
0
0
13
7
0
0
0
0
50
7
% R
% Ser:
7
13
0
0
13
7
7
13
38
13
7
13
25
0
44
% S
% Thr:
0
13
7
7
7
0
0
32
0
7
7
44
7
0
13
% T
% Val:
7
13
0
13
7
38
0
7
0
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
7
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _