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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 26.36
Human Site: T731 Identified Species: 38.67
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 T731 V A D K R K E T Q S R G M E G
Chimpanzee Pan troglodytes XP_518055 1227 139177 T724 V T D K R K E T Q S H G K E G
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 T731 V A D K R K E T Q S R G M E G
Dog Lupus familis XP_549061 1234 139874 T732 V A D K R K E T Q S R G M E G
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 T732 V A E K R K E T Q S R G M E S
Rat Rattus norvegicus Q7M6Z5 1394 158861 Q878 A E V K R D Q Q K L K E L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S737 A A D K R K E S Q N R G M E G
Frog Xenopus laevis Q91784 1226 138905 S734 A M E K R K D S Q S K G M E G
Zebra Danio Brachydanio rerio Q58G59 1363 154819 R816 Q V L K Q K Q R D T A Q L A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 A338 T L T T L R Y A S R A K S I Q
Honey Bee Apis mellifera XP_395595 1064 123475 K618 T E Q D K I V K M K D K Q D Q
Nematode Worm Caenorhab. elegans P46873 699 78760 T253 G D R L K E A T K I N L S L S
Sea Urchin Strong. purpuratus P46872 699 78679 R253 V D L A G S E R Q T K T G A T
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 I591 D G Q K L Q D I H A Q K L K T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 L588 H A Q N L K A L E A Q I L D L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 L482 L K D H D S K L G K E N E R L
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 80 100 100 N.A. 86.6 13.3 N.A. N.A. 80 60 13.3 N.A. 0 0 6.6 20
P-Site Similarity: 100 80 100 100 N.A. 93.3 46.6 N.A. N.A. 93.3 86.6 40 N.A. 6.6 13.3 26.6 33.3
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 46.6 N.A. N.A. 46.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 38 0 7 0 0 13 7 0 13 13 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 13 38 7 7 7 13 0 7 0 7 0 0 13 0 % D
% Glu: 0 13 13 0 0 7 44 0 7 0 7 7 7 44 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 7 0 0 7 0 0 0 7 0 0 44 7 0 38 % G
% His: 7 0 0 7 0 0 0 0 7 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 7 0 7 0 7 0 7 0 % I
% Lys: 0 7 0 63 13 57 7 7 13 13 19 19 7 7 0 % K
% Leu: 7 7 13 7 19 0 0 13 0 7 0 7 25 7 19 % L
% Met: 0 7 0 0 0 0 0 0 7 0 0 0 38 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 7 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 19 0 7 7 13 7 50 0 13 7 7 7 13 % Q
% Arg: 0 0 7 0 50 7 0 13 0 7 32 0 0 7 0 % R
% Ser: 0 0 0 0 0 13 0 13 7 38 0 0 13 0 19 % S
% Thr: 13 7 7 7 0 0 0 38 0 13 0 7 0 0 13 % T
% Val: 38 7 7 0 0 0 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _