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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 15.15
Human Site: Y1200 Identified Species: 22.22
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 Y1200 L K H V A T E Y Q E N K A P G
Chimpanzee Pan troglodytes XP_518055 1227 139177 Y1195 S K H G A T E Y Q Q N K P P G
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 Y1202 L K H V A T E Y Q E N K A P G
Dog Lupus familis XP_549061 1234 139874 S1202 L K H V A T E S Q E N K A P G
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 Q1200 K S I A S E S Q E N K A I G K
Rat Rattus norvegicus Q7M6Z5 1394 158861 K1355 L Q G V K P V K V C R R E L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S1192 L L V R D E E S Q E N Q L P F
Frog Xenopus laevis Q91784 1226 138905 N1196 S V M E S Q E N Q T S I L T K
Zebra Danio Brachydanio rerio Q58G59 1363 154819 S1325 G M N S T H W S G S T S L P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 N754 G L P S A A S N L D S N R R P
Honey Bee Apis mellifera XP_395595 1064 123475 L1034 C D E L I A G L I V M L S A S
Nematode Worm Caenorhab. elegans P46873 699 78760 G669 S K T P T F D G L V N G V V Y
Sea Urchin Strong. purpuratus P46872 699 78679 K669 K Y K P S Q G K S G R P K T S
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 W1016 W K R S H H Q W L L Q F K W K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 K1005 Q F K W K W Q K P W R L S E W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 V898 L R G G G D A V A G A T A T N
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 73.3 100 93.3 N.A. 0 13.3 N.A. N.A. 40 13.3 6.6 N.A. 6.6 0 13.3 0
P-Site Similarity: 100 80 100 93.3 N.A. 13.3 26.6 N.A. N.A. 46.6 26.6 13.3 N.A. 20 13.3 20 6.6
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 32 13 7 0 7 0 7 7 25 7 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 7 7 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 7 7 0 13 38 0 7 25 0 0 7 7 0 % E
% Phe: 0 7 0 0 0 7 0 0 0 0 0 7 0 0 7 % F
% Gly: 13 0 13 13 7 0 13 7 7 13 0 7 0 7 25 % G
% His: 0 0 25 0 7 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 7 0 0 0 7 0 0 7 7 0 0 % I
% Lys: 13 38 13 0 13 0 0 19 0 0 7 25 13 0 19 % K
% Leu: 38 13 0 7 0 0 0 7 19 7 0 13 19 7 0 % L
% Met: 0 7 7 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 13 0 7 38 7 0 0 7 % N
% Pro: 0 0 7 13 0 7 0 0 7 0 0 7 7 38 7 % P
% Gln: 7 7 0 0 0 13 13 7 38 7 7 7 0 0 0 % Q
% Arg: 0 7 7 7 0 0 0 0 0 0 19 7 7 7 7 % R
% Ser: 19 7 0 19 19 0 13 19 7 7 13 7 13 0 13 % S
% Thr: 0 0 7 0 13 25 0 0 0 7 7 7 0 19 0 % T
% Val: 0 7 7 25 0 0 7 7 7 13 0 0 7 7 7 % V
% Trp: 7 0 0 7 0 7 7 7 0 7 0 0 0 7 7 % W
% Tyr: 0 7 0 0 0 0 0 19 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _