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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4A
All Species:
36.97
Human Site:
Y144
Identified Species:
54.22
UniProt:
O95239
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95239
NP_036442.3
1232
139881
Y144
K
V
S
Y
L
E
I
Y
N
E
E
I
L
D
L
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
Y144
K
V
S
F
L
E
I
Y
N
E
E
I
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S144
K
V
S
Y
L
E
V
S
N
L
R
L
I
I
L
Dog
Lupus familis
XP_549061
1234
139874
Y144
K
V
S
Y
L
E
I
Y
N
E
E
I
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
Y144
K
V
S
Y
L
E
I
Y
N
E
E
I
L
D
L
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
Y139
K
V
S
Y
I
E
V
Y
K
E
D
L
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
Y144
K
V
S
Y
L
E
I
Y
N
E
D
I
L
D
L
Frog
Xenopus laevis
Q91784
1226
138905
Y143
K
V
S
Y
L
E
I
Y
N
E
E
I
L
D
L
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
Y149
R
V
S
Y
M
E
V
Y
K
E
V
F
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
Honey Bee
Apis mellifera
XP_395595
1064
123475
Y137
T
V
S
F
M
E
L
Y
Q
E
Q
L
Y
D
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Sea Urchin
Strong. purpuratus
P46872
699
78679
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
C125
G
T
G
F
K
D
G
C
Q
M
G
I
I
P
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199593
1035
116715
K123
V
M
N
A
L
F
T
K
I
E
T
L
K
Q
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
E21
F
R
P
Q
N
R
V
E
I
E
S
G
G
Q
P
Conservation
Percent
Protein Identity:
100
93.1
96.4
94.8
N.A.
87
27
N.A.
N.A.
74.5
68.5
25.8
N.A.
26.9
36.8
27.1
27.3
Protein Similarity:
100
95.6
97.2
97
N.A.
92.7
47.6
N.A.
N.A.
85.9
82.1
45.1
N.A.
41.4
56.3
38.4
39.3
P-Site Identity:
100
93.3
53.3
100
N.A.
100
60
N.A.
N.A.
93.3
100
53.3
N.A.
0
46.6
0
0
P-Site Similarity:
100
100
73.3
100
N.A.
100
86.6
N.A.
N.A.
100
100
73.3
N.A.
0
80
0
0
Percent
Protein Identity:
33.2
N.A.
N.A.
32.7
N.A.
26.7
Protein Similarity:
51
N.A.
N.A.
51
N.A.
44.5
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
13
0
0
57
0
% D
% Glu:
0
0
0
0
0
63
0
7
0
69
32
0
0
0
0
% E
% Phe:
7
0
0
19
0
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
7
0
0
0
7
0
0
0
7
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
38
0
13
0
0
44
13
7
0
% I
% Lys:
50
0
0
0
7
0
0
7
13
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
50
0
7
0
0
7
0
25
38
0
63
% L
% Met:
0
7
0
0
13
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
44
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
0
0
7
0
0
0
0
13
0
7
0
0
13
13
% Q
% Arg:
7
7
0
0
0
7
0
0
0
0
7
0
13
0
0
% R
% Ser:
0
0
63
0
0
0
0
7
0
0
7
0
0
0
0
% S
% Thr:
7
7
0
0
0
0
7
0
0
0
7
0
0
0
0
% T
% Val:
7
63
0
0
0
0
25
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
57
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _