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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 29.7
Human Site: Y869 Identified Species: 43.56
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 Y869 E A K C A L K Y L I G E L V S
Chimpanzee Pan troglodytes XP_518055 1227 139177 Y862 E A K C A L K Y L I G E L V S
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 Y869 E A K C A L K Y L I G E L V S
Dog Lupus familis XP_549061 1234 139874 Y870 E A K C A L K Y L I G E L V S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 Y870 E A K C A I K Y L V G E L V S
Rat Rattus norvegicus Q7M6Z5 1394 158861 S1036 Q L Q R Q R N S V D E K L R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Y873 E A K C A L K Y L L G E L V S
Frog Xenopus laevis Q91784 1226 138905 Y871 E A K C A L K Y L I T E L V S
Zebra Danio Brachydanio rerio Q58G59 1363 154819 W962 A K K E A L L W E R S G L E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L459 N S K L A A K L A E L E G Q L
Honey Bee Apis mellifera XP_395595 1064 123475 Q739 K I K S W L T Q E I E I L I S
Nematode Worm Caenorhab. elegans P46873 699 78760 E374 A Q D A F S I E E E R K K L R
Sea Urchin Strong. purpuratus P46872 699 78679 S374 L K K Q I S E S G E G L D D D
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 S718 L L E A R K S S A R D N S A I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 R709 E A R K S S P R E H S A G T N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 P603 S A G D A I P P E D I K A L R
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 100 100 100 N.A. 86.6 6.6 N.A. N.A. 93.3 93.3 33.3 N.A. 26.6 33.3 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. N.A. 100 93.3 40 N.A. 33.3 46.6 13.3 20
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 0 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 6.6 N.A. N.A. 33.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 57 0 13 63 7 0 0 13 0 0 7 7 7 0 % A
% Cys: 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 0 0 13 7 0 7 7 7 % D
% Glu: 50 0 7 7 0 0 7 7 32 19 13 50 0 7 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 7 0 44 7 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 7 0 0 7 13 7 0 0 38 7 7 0 7 7 % I
% Lys: 7 13 69 7 0 7 50 0 0 0 0 19 7 0 0 % K
% Leu: 13 13 0 7 0 50 7 7 44 7 7 7 63 13 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 7 0 0 7 % N
% Pro: 0 0 0 0 0 0 13 7 0 0 0 0 0 0 0 % P
% Gln: 7 7 7 7 7 0 0 7 0 0 0 0 0 7 0 % Q
% Arg: 0 0 7 7 7 7 0 7 0 13 7 0 0 7 13 % R
% Ser: 7 7 0 7 7 19 7 19 0 0 13 0 7 0 57 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 7 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 7 7 0 0 0 44 0 % V
% Trp: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _