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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST2 All Species: 23.64
Human Site: S192 Identified Species: 37.14
UniProt: O95251 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95251 NP_008998.1 611 70642 S192 C P T P G C N S L G H L T G K
Chimpanzee Pan troglodytes XP_511869 806 91579 S387 C P T P G C N S L G H L T G K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548192 555 64081 C153 R H F S I S G C P L Y H N L S
Cat Felis silvestris
Mouse Mus musculus Q5SVQ0 613 70623 S194 C P T P G C N S L G H L T G K
Rat Rattus norvegicus Q810T5 612 70496 S193 C P T P G C N S L G H L T G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026512 611 70527 S192 C P T P G C N S L G H L T G K
Frog Xenopus laevis NP_001079995 617 71123 S192 C P T P G C N S L G H L T G K
Zebra Danio Brachydanio rerio NP_997800 568 65560 I166 K H E R H F A I S G C P L Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 P139 T G A S G S V P P P A G I P N
Honey Bee Apis mellifera XP_392324 916 101344 R484 L A P T C D S R G H L S G K L
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 R56 A E V I S R C R A A N G S I K
Sea Urchin Strong. purpuratus XP_782361 504 58083 K102 K K G R K R G K S E T H H S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 A43 P P L T P D Q A I I E S D P S
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 I43 R L A E I L S I N T R K A P P
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 T104 K T K K N N S T V S K K Q P S
Conservation
Percent
Protein Identity: 100 75.8 N.A. 89.3 N.A. 99 99 N.A. N.A. 97.8 93.1 76.4 N.A. 33.7 34 30.9 39.2
Protein Similarity: 100 75.8 N.A. 89.5 N.A. 99 99 N.A. N.A. 98.5 95.9 83.4 N.A. 49.5 48.1 48.6 53.8
P-Site Identity: 100 100 N.A. 0 N.A. 100 100 N.A. N.A. 100 100 6.6 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 N.A. 6.6 N.A. 100 100 N.A. N.A. 100 100 6.6 N.A. 6.6 6.6 20 0
Percent
Protein Identity: N.A. N.A. N.A. 36.3 31.9 31.2
Protein Similarity: N.A. N.A. N.A. 50.4 47.6 47.4
P-Site Identity: N.A. N.A. N.A. 6.6 0 0
P-Site Similarity: N.A. N.A. N.A. 20 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 14 0 0 0 7 7 7 7 7 0 7 0 0 % A
% Cys: 40 0 0 0 7 40 7 7 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 14 0 0 0 0 0 0 7 0 7 % D
% Glu: 0 7 7 7 0 0 0 0 0 7 7 0 0 0 0 % E
% Phe: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 0 47 0 14 0 7 47 0 14 7 40 0 % G
% His: 0 14 0 0 7 0 0 0 0 7 40 14 7 0 7 % H
% Ile: 0 0 0 7 14 0 0 14 7 7 0 0 7 7 0 % I
% Lys: 20 7 7 7 7 0 0 7 0 0 7 14 0 7 47 % K
% Leu: 7 7 7 0 0 7 0 0 40 7 7 40 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 7 40 0 7 0 7 0 7 0 7 % N
% Pro: 7 47 7 40 7 0 0 7 14 7 0 7 0 27 7 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % Q
% Arg: 14 0 0 14 0 14 0 14 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 14 7 14 20 40 14 7 0 14 7 7 20 % S
% Thr: 7 7 40 14 0 0 0 7 0 7 7 0 40 0 0 % T
% Val: 0 0 7 0 0 0 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _