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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST2 All Species: 25.15
Human Site: S53 Identified Species: 39.52
UniProt: O95251 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95251 NP_008998.1 611 70642 S53 S A R L S Q S S Q D S S P V R
Chimpanzee Pan troglodytes XP_511869 806 91579 S248 S A R L S Q S S Q D S S P V R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548192 555 64081 S14 L Q R N A G S S S D G T E D S
Cat Felis silvestris
Mouse Mus musculus Q5SVQ0 613 70623 S55 S A R L S Q S S Q D S S P V R
Rat Rattus norvegicus Q810T5 612 70496 S54 S A R L S Q S S Q D S S P V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026512 611 70527 S53 S A R L S Q S S Q D S S P V R
Frog Xenopus laevis NP_001079995 617 71123 S53 T A R L S Q S S Q D S S P V G
Zebra Danio Brachydanio rerio NP_997800 568 65560 S27 N T E R T A G S S S D G T A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216
Honey Bee Apis mellifera XP_392324 916 101344 A345 E D E A D A S A S E K E M D E
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125
Sea Urchin Strong. purpuratus XP_782361 504 58083
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594
Red Bread Mold Neurospora crassa Q7S9B6 506 58788
Conservation
Percent
Protein Identity: 100 75.8 N.A. 89.3 N.A. 99 99 N.A. N.A. 97.8 93.1 76.4 N.A. 33.7 34 30.9 39.2
Protein Similarity: 100 75.8 N.A. 89.5 N.A. 99 99 N.A. N.A. 98.5 95.9 83.4 N.A. 49.5 48.1 48.6 53.8
P-Site Identity: 100 100 N.A. 26.6 N.A. 100 100 N.A. N.A. 100 86.6 6.6 N.A. 0 6.6 0 0
P-Site Similarity: 100 100 N.A. 40 N.A. 100 100 N.A. N.A. 100 93.3 20 N.A. 0 20 0 0
Percent
Protein Identity: N.A. N.A. N.A. 36.3 31.9 31.2
Protein Similarity: N.A. N.A. N.A. 50.4 47.6 47.4
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 0 7 7 14 0 7 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 0 0 0 0 47 7 0 0 14 7 % D
% Glu: 7 0 14 0 0 0 0 0 0 7 0 7 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 7 0 0 0 7 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 7 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % P
% Gln: 0 7 0 0 0 40 0 0 40 0 0 0 0 0 0 % Q
% Arg: 0 0 47 7 0 0 0 0 0 0 0 0 0 0 34 % R
% Ser: 34 0 0 0 40 0 54 54 20 7 40 40 0 0 7 % S
% Thr: 7 7 0 0 7 0 0 0 0 0 0 7 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _