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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
23.94
Human Site:
S594
Identified Species:
37.62
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S594
K
E
A
K
R
S
N
S
N
K
T
M
D
P
S
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S789
K
E
A
K
R
S
N
S
N
K
T
M
D
P
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
N539
E
A
K
R
S
N
S
N
K
T
M
D
P
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S596
K
E
A
K
R
S
N
S
N
K
T
M
D
P
S
Rat
Rattus norvegicus
Q810T5
612
70496
S595
K
E
A
K
R
S
N
S
N
K
T
M
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S594
K
E
A
K
R
S
N
S
N
K
I
M
D
P
S
Frog
Xenopus laevis
NP_001079995
617
71123
S600
K
D
A
K
R
T
N
S
N
K
A
M
D
P
G
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
S552
K
E
T
K
R
G
N
S
K
T
I
D
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
D525
D
K
R
K
I
R
I
D
S
K
C
L
H
W
T
Honey Bee
Apis mellifera
XP_392324
916
101344
V892
R
V
K
R
R
G
P
V
Y
K
E
I
D
P
E
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
L442
T
R
I
N
P
A
A
L
Q
W
R
P
K
E
Y
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
G488
L
P
Q
Y
M
R
Q
G
Y
G
K
M
L
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
L429
K
A
A
G
R
G
G
L
D
V
D
A
S
K
L
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
L429
R
T
I
D
P
N
R
L
I
W
K
P
P
V
F
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
I490
R
L
I
D
P
E
R
I
Q
W
K
P
P
V
F
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
93.3
73.3
46.6
N.A.
13.3
26.6
0
6.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
46.6
N.A.
40
46.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
47
0
0
7
7
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% C
% Asp:
7
7
0
14
0
0
0
7
7
0
7
14
47
0
7
% D
% Glu:
7
40
0
0
0
7
0
0
0
0
7
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% F
% Gly:
0
0
0
7
0
20
7
7
0
7
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
20
0
7
0
7
7
7
0
14
7
0
7
0
% I
% Lys:
54
7
14
54
0
0
0
0
14
54
20
0
7
7
0
% K
% Leu:
7
7
0
0
0
0
0
20
0
0
0
7
7
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
7
47
0
0
0
% M
% Asn:
0
0
0
7
0
14
47
7
40
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
20
0
7
0
0
0
0
20
27
47
0
% P
% Gln:
0
0
7
0
0
0
7
0
14
0
0
0
0
0
0
% Q
% Arg:
20
7
7
14
60
14
14
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
7
34
7
47
7
0
0
0
7
7
40
% S
% Thr:
7
7
7
0
0
7
0
0
0
14
27
0
0
0
7
% T
% Val:
0
7
0
0
0
0
0
7
0
7
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
20
0
0
0
7
0
% W
% Tyr:
0
0
0
7
0
0
0
0
14
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _