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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
8.48
Human Site:
T1252
Identified Species:
16.97
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
T1252
E
A
P
W
R
L
P
T
C
A
A
Q
P
P
W
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
D1021
Y
C
L
R
Y
R
E
D
L
D
F
V
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
S1121
R
L
E
S
A
S
Y
S
S
V
C
S
H
M
A
Dog
Lupus familis
XP_547113
1504
165780
A1253
E
A
P
W
R
L
P
A
C
A
A
R
S
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
T1247
E
A
P
W
R
L
P
T
C
A
A
Q
P
L
W
Rat
Rattus norvegicus
O88269
1502
164977
S1251
E
A
P
W
R
L
P
S
S
A
A
Q
P
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
E1286
E
A
P
W
Q
I
E
E
T
A
P
A
P
D
W
Chicken
Gallus gallus
Q5F364
1525
170953
E1274
E
A
E
W
S
I
E
E
T
A
P
A
S
T
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
N1267
E
A
E
W
K
L
E
N
S
N
L
P
P
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
E1064
S
F
V
I
Q
P
R
E
K
V
G
I
V
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
E1284
E
A
K
W
E
I
K
E
S
R
P
P
P
N
W
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
G1259
E
A
P
L
I
V
E
G
H
R
P
P
K
E
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
80
N.A.
93.3
80
N.A.
46.6
33.3
N.A.
40
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
6.6
86.6
N.A.
93.3
86.6
N.A.
60
40
N.A.
46.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
0
0
9
0
0
9
0
50
34
17
0
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
25
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% D
% Glu:
75
0
25
0
9
0
42
34
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
9
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% H
% Ile:
0
0
0
9
9
25
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
9
0
9
0
9
0
9
0
0
0
9
0
0
% K
% Leu:
0
9
9
9
0
42
0
0
9
0
9
0
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% N
% Pro:
0
0
50
0
0
9
34
0
0
0
34
25
50
17
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
25
0
0
0
% Q
% Arg:
9
0
0
9
34
9
9
0
0
17
0
9
0
9
9
% R
% Ser:
9
0
0
9
9
9
0
17
34
0
0
9
17
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
17
0
0
0
0
9
0
% T
% Val:
0
0
9
0
0
9
0
0
0
17
0
9
9
0
0
% V
% Trp:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
75
% W
% Tyr:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _