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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL18RAP
All Species:
9.09
Human Site:
S469
Identified Species:
25
UniProt:
O95256
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95256
NP_003844.1
599
68310
S469
V
Y
A
E
D
I
V
S
I
I
K
R
S
R
R
Chimpanzee
Pan troglodytes
XP_001163370
599
68242
S469
V
Y
A
E
D
I
V
S
I
I
K
R
S
R
R
Rhesus Macaque
Macaca mulatta
P59822
570
65375
D441
G
Y
K
L
C
I
F
D
R
D
S
L
P
G
G
Dog
Lupus familis
XP_538448
671
75598
W506
A
F
I
S
Y
A
K
W
S
S
F
E
N
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B1
614
70075
S468
V
Y
A
D
D
I
V
S
I
I
K
K
S
R
R
Rat
Rattus norvegicus
P59824
696
79753
R465
T
Y
I
E
D
V
A
R
C
V
D
Q
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514638
505
57459
R377
V
T
V
I
K
Q
S
R
R
G
I
F
I
L
S
Chicken
Gallus gallus
XP_001234110
645
74018
E514
G
Y
K
L
C
I
L
E
R
D
I
L
P
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B6ZK77
700
80295
R465
T
Y
I
E
D
V
A
R
C
V
D
Q
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
26
63.1
N.A.
64
25.1
N.A.
45
37.6
N.A.
25.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
46.5
72.7
N.A.
77.6
42.2
N.A.
57.4
53.7
N.A.
42.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
86.6
33.3
N.A.
6.6
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
60
N.A.
6.6
20
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
34
0
0
12
23
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
23
0
0
0
23
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
56
0
0
12
0
23
23
0
0
0
0
% D
% Glu:
0
0
0
45
0
0
0
12
0
0
0
12
0
12
0
% E
% Phe:
0
12
0
0
0
0
12
0
0
0
12
12
0
0
0
% F
% Gly:
23
0
0
0
0
0
0
0
0
12
0
0
0
23
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
12
0
56
0
0
34
34
23
0
12
0
0
% I
% Lys:
0
0
23
0
12
0
12
0
0
0
34
12
0
23
0
% K
% Leu:
0
0
0
23
0
0
12
0
0
0
0
23
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
23
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
34
34
0
0
23
0
34
56
% R
% Ser:
0
0
0
12
0
0
12
34
12
12
12
0
56
0
12
% S
% Thr:
23
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
45
0
12
0
0
23
34
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
78
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _