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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A14 All Species: 14.55
Human Site: Y125 Identified Species: 26.67
UniProt: O95258 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95258 NP_003942.1 325 36202 Y125 G T I K I G I Y Q S L K R L F
Chimpanzee Pan troglodytes XP_001140712 353 39208 Y122 G T I K I G I Y Q S L K R L F
Rhesus Macaque Macaca mulatta XP_001094996 291 32463 V98 Q S L K R L F V E R P E D E T
Dog Lupus familis XP_852497 325 36209 Y125 G T I K I G I Y Q S L K R L F
Cat Felis silvestris
Mouse Mus musculus Q9Z2B2 325 36267 Y125 G T I K I G I Y Q S L K R L F
Rat Rattus norvegicus Q5PQM9 291 32346 V98 Q S L K R L A V E R P E D E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514476 291 32446 V98 Q S L K R L F V E R P E D E T
Chicken Gallus gallus NP_001012901 284 31431 S92 I K I G I Y Q S L K R L F V D
Frog Xenopus laevis Q6GQ22 291 32540 V98 Q S L K R L F V D C P E D E T
Zebra Danio Brachydanio rerio Q9W720 310 33554 D113 Q F Y T K G S D H A G I G S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648501 303 33474 E111 L I N E D G S E R V W S N I L
Honey Bee Apis mellifera XP_397152 299 33272 D107 A M N K W E T D D L V I I N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32332 324 35135 D119 L N Q L F F P D Q E P H K V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.2 72.9 98.1 N.A. 97.5 72 N.A. 70.4 78.1 71.6 36.6 N.A. 52.6 52.9 N.A. N.A.
Protein Similarity: 100 91.2 80.9 98.7 N.A. 99.3 80 N.A. 80.6 83.3 80.6 56.6 N.A. 66.4 68 N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 6.6 N.A. 6.6 13.3 6.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 100 33.3 N.A. 33.3 20 26.6 13.3 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 24 16 0 0 0 31 0 8 % D
% Glu: 0 0 0 8 0 8 0 8 24 8 0 31 0 31 0 % E
% Phe: 0 8 0 0 8 8 24 0 0 0 0 0 8 0 31 % F
% Gly: 31 0 0 8 0 47 0 0 0 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 8 8 39 0 39 0 31 0 0 0 0 16 8 8 8 % I
% Lys: 0 8 0 70 8 0 0 0 0 8 0 31 8 0 0 % K
% Leu: 16 0 31 8 0 31 0 0 8 8 31 8 0 31 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 39 0 0 0 0 % P
% Gln: 39 0 8 0 0 0 8 0 39 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 31 0 0 0 8 24 8 0 31 0 8 % R
% Ser: 0 31 0 0 0 0 16 8 0 31 0 8 0 8 0 % S
% Thr: 0 31 0 8 0 0 8 0 0 0 0 0 0 0 31 % T
% Val: 0 0 0 0 0 0 0 31 0 8 8 0 0 16 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 0 31 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _