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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A14 All Species: 9.7
Human Site: Y276 Identified Species: 17.78
UniProt: O95258 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95258 NP_003942.1 325 36202 Y276 I V G H V D L Y K G T V D G I
Chimpanzee Pan troglodytes XP_001140712 353 39208 C273 H F V S S F T C G L A G A L A
Rhesus Macaque Macaca mulatta XP_001094996 291 32463 L249 Y T G T L D C L L Q T W K N E
Dog Lupus familis XP_852497 325 36209 Y276 I V G H V D L Y K G T L D G I
Cat Felis silvestris
Mouse Mus musculus Q9Z2B2 325 36267 Y276 I V G H V D L Y K G T L D G I
Rat Rattus norvegicus Q5PQM9 291 32346 L249 Y K G T L D C L L Q T W K N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514476 291 32446 L249 Y L G T L D C L L Q M W K N E
Chicken Gallus gallus NP_001012901 284 31431 G243 G S V E L Y K G T L D G L V K
Frog Xenopus laevis Q6GQ22 291 32540 L249 Y K G T L D C L L Q T W K N E
Zebra Danio Brachydanio rerio Q9W720 310 33554 K264 C A V A M L T K K G P K A F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648501 303 33474 C262 L Y S G S L D C A V Q T I R N
Honey Bee Apis mellifera XP_397152 299 33272 T258 S I D C F V Q T F K N E G F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32332 324 35135 D270 D L Y K G P I D C L V K T V R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.2 72.9 98.1 N.A. 97.5 72 N.A. 70.4 78.1 71.6 36.6 N.A. 52.6 52.9 N.A. N.A.
Protein Similarity: 100 91.2 80.9 98.7 N.A. 99.3 80 N.A. 80.6 83.3 80.6 56.6 N.A. 66.4 68 N.A. N.A.
P-Site Identity: 100 0 20 93.3 N.A. 93.3 20 N.A. 13.3 0 20 13.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 0 26.6 100 N.A. 100 26.6 N.A. 26.6 6.6 26.6 20 N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 8 0 8 0 16 0 8 % A
% Cys: 8 0 0 8 0 0 31 16 8 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 54 8 8 0 0 8 0 24 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 31 % E
% Phe: 0 8 0 0 8 8 0 0 8 0 0 0 0 16 8 % F
% Gly: 8 0 54 8 8 0 0 8 8 31 0 16 8 24 0 % G
% His: 8 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 24 8 0 0 0 0 8 0 0 0 0 0 8 0 24 % I
% Lys: 0 16 0 8 0 0 8 8 31 8 0 16 31 0 8 % K
% Leu: 8 16 0 0 39 16 24 31 31 24 0 16 8 8 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 31 8 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 31 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % R
% Ser: 8 8 8 8 16 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 31 0 0 16 8 8 0 47 8 8 0 0 % T
% Val: 0 24 24 0 24 8 0 0 0 8 8 8 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 31 0 0 0 % W
% Tyr: 31 8 8 0 0 8 0 24 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _