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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATE1 All Species: 24.85
Human Site: S278 Identified Species: 45.56
UniProt: O95260 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95260 NP_001001976.1 518 59090 S278 E V R V V R S S P P S S Q F K
Chimpanzee Pan troglodytes XP_508079 579 64705 S339 E V R V V R S S P P S S Q F K
Rhesus Macaque Macaca mulatta XP_001101531 518 59066 S278 E V R V V R S S P P S S Q F K
Dog Lupus familis XP_544049 522 59741 S282 E V R V V R S S P P S S Q F K
Cat Felis silvestris
Mouse Mus musculus Q9Z2A5 516 59188 S276 E V R V V R S S P P S P Q F R
Rat Rattus norvegicus NP_001099770 509 58198 S269 E S L P E D A S H K L E V R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073201 484 54975 E244 E G S P L Q A E H Q A L L L Q
Frog Xenopus laevis NP_001093364 514 58180 S274 E V K L V P V S M E D P E F V
Zebra Danio Brachydanio rerio NP_001082937 496 56191 N256 E V R L V R S N P P S P Q F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O96539 484 55298 L241 K H R L K L R L I H V Y D D E
Honey Bee Apis mellifera XP_395484 513 59866 S270 Q L K L V R T S P M S S G Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789819 540 60914 N275 E I K L V R S N P M S A E F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZT48 632 71523 H319 R K R K L E I H L K R S S F D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.9 97.6 88.6 N.A. 80.8 81.2 N.A. N.A. 63.9 57.1 56.5 N.A. 38.6 45.7 N.A. 44.4
Protein Similarity: 100 86.8 98.6 92.3 N.A. 88.2 88.6 N.A. N.A. 74.9 72.5 72.7 N.A. 57.5 63.7 N.A. 61.1
P-Site Identity: 100 100 100 100 N.A. 86.6 13.3 N.A. N.A. 6.6 33.3 80 N.A. 6.6 40 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. N.A. 40 53.3 93.3 N.A. 26.6 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 31.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 8 0 8 8 8 % D
% Glu: 77 0 0 0 8 8 0 8 0 8 0 8 16 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 8 0 0 0 0 0 8 16 8 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 8 8 24 8 8 0 0 0 0 16 0 0 0 0 39 % K
% Leu: 0 8 8 39 16 8 0 8 8 0 8 8 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 8 16 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 16 0 8 0 0 62 47 0 24 0 0 0 % P
% Gln: 8 0 0 0 0 8 0 0 0 8 0 0 47 0 8 % Q
% Arg: 8 0 62 0 0 62 8 0 0 0 8 0 0 8 8 % R
% Ser: 0 8 8 0 0 0 54 62 0 0 62 47 8 0 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % T
% Val: 0 54 0 39 70 0 8 0 0 0 8 0 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _