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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE8B
All Species:
4.55
Human Site:
S517
Identified Species:
14.29
UniProt:
O95263
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95263
NP_001025022.1
885
98979
S517
T
D
G
L
R
R
L
S
G
N
E
Y
V
F
T
Chimpanzee
Pan troglodytes
XP_517695
907
102819
S539
T
D
G
L
R
R
L
S
G
N
E
Y
V
F
T
Rhesus Macaque
Macaca mulatta
XP_001101740
752
84621
I428
E
E
S
W
D
F
N
I
F
E
L
E
A
V
T
Dog
Lupus familis
XP_546056
836
94573
N511
N
E
E
S
W
E
F
N
I
F
E
L
E
A
V
Cat
Felis silvestris
Mouse
Mus musculus
O88502
823
93153
E499
Q
W
D
F
D
I
F
E
L
E
V
A
T
Q
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413834
859
97059
M518
P
P
R
I
A
Q
A
M
E
N
E
E
H
W
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920432
784
88757
A460
N
I
L
E
L
E
A
A
T
H
K
R
P
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N2V9
760
84862
N436
R
V
S
A
D
V
K
N
A
L
E
N
D
N
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
81.1
85.6
N.A.
61.1
N.A.
N.A.
N.A.
68.8
N.A.
69.1
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
100
88.9
82.5
88.5
N.A.
75.1
N.A.
N.A.
N.A.
81.4
N.A.
79.3
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
0
N.A.
N.A.
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
0
25
13
13
0
0
13
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
0
25
13
0
38
0
0
0
0
0
0
0
13
0
13
% D
% Glu:
13
25
13
13
0
25
0
13
13
25
63
25
13
0
0
% E
% Phe:
0
0
0
13
0
13
25
0
13
13
0
0
0
25
0
% F
% Gly:
0
0
25
0
0
0
0
0
25
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
13
0
0
% H
% Ile:
0
13
0
13
0
13
0
13
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% K
% Leu:
0
0
13
25
13
0
25
0
13
13
13
13
0
13
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
0
0
13
25
0
38
0
13
0
13
13
% N
% Pro:
13
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
13
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% Q
% Arg:
13
0
13
0
25
25
0
0
0
0
0
13
0
0
0
% R
% Ser:
0
0
25
13
0
0
0
25
0
0
0
0
0
0
13
% S
% Thr:
25
0
0
0
0
0
0
0
13
0
0
0
13
0
38
% T
% Val:
0
13
0
0
0
13
0
0
0
0
13
0
25
13
13
% V
% Trp:
0
13
0
13
13
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _